Tao Liang

TL;DR: It is demonstrated that puerarin successfully reverses hepatotoxicity in CCl(4)-induced HF rats via the underlying mechanisms of regulating serum enzymes and attenuating TNF-α/NF-κB pathway for anti-inflammation response, as well as improving metabolic function in liver tissue.

TL;DR: It is demonstrated that cinnamon polyphenols can exert the hypoglycemic and hypolipidemic effects through the mechanisms that may be associated with repairing pancreatic beta cells in diabetic mice and improving its anti-oxidative capacity, as well as attenuating cytotoxicity via inhibition of iNOS, NF-κB activation.

TL;DR: Taking together, PR could attenuate the CCl4-induced toxicity in the hepatocytes of HF rats and played a protective role in the liver tissue probably through regulating the PPAR-γ expression and blocking the PI3K/Akt pathway to inhibit the excessive deposition of collagen.

TL;DR: The results suggest that RMP plays the blood glucose-lowering and metabolism-normalizing roles, and it may improve the function of pancreas through inhibiting the inflammatory response and attenuating the oxidative stress in Pancreas tissue.

TL;DR: The present study demonstrates the hypoglycemic and renal protective effects of PR in DN mice, which support its anti-diabetic property.