T
Tapan A. Padhya
Researcher at University of South Florida
Publications - 88
Citations - 5077
Tapan A. Padhya is an academic researcher from University of South Florida. The author has contributed to research in topics: Obstructive sleep apnea & Medicine. The author has an hindex of 27, co-authored 79 publications receiving 4304 citations. Previous affiliations of Tapan A. Padhya include University of Louisville & Moffitt Cancer Center.
Papers
More filters
Journal ArticleDOI
HIF-1α regulates function and differentiation of myeloid-derived suppressor cells in the tumor microenvironment
Cesar A. Corzo,Thomas Condamine,Lily Lu,Matthew J. Cotter,Je In Youn,Pingyan Cheng,Hyun Il Cho,Esteban Celis,David G. Quiceno,Tapan A. Padhya,Thomas V. McCaffrey,Judith C. McCaffrey,Dmitry I. Gabrilovich +12 more
TL;DR: The hypoxic environment of tumors dictates the phenotype of local myeloid-derived suppressor cells (MDSCs) via HIF-1a expression; hypoxia converts splenic MDSCs from specific into nonspecific suppressors.
Journal ArticleDOI
Mechanism Regulating Reactive Oxygen Species in Tumor-Induced Myeloid-Derived Suppressor Cells
Cesar A. Corzo,Matthew J. Cotter,Pingyan Cheng,Fendong Cheng,Sergei Kusmartsev,Eduardo M. Sotomayor,Tapan A. Padhya,Thomas V. McCaffrey,Judith C. McCaffrey,Dmitry I. Gabrilovich +9 more
TL;DR: A substantial up-regulation of ROS by MDSC is observed in all of seven different tumor models and in patients with head and neck cancer, mediated by up-regulated activity of NADPH oxidase (NOX2) and may open new opportunities for therapeutic regulation of these cells in cancer.
Journal ArticleDOI
Lipid accumulation and dendritic cell dysfunction in cancer
Donna L. Herber,Wei Cao,Yulia Nefedova,Sergey V. Novitskiy,Srinivas Nagaraj,Vladimir A. Tyurin,Alex Corzo,Hyun Ii Cho,Esteban Celis,Brianna Lennox,Stella C. Knight,Tapan A. Padhya,Thomas V. McCaffrey,Judith C. McCaffrey,Scott J. Antonia,Mayer Fishman,Robert L. Ferris,Valerian E. Kagan,Dmitry I. Gabrilovich +18 more
TL;DR: In this article, a substantial proportion of Dendritic cells (DCs) in tumor-bearing mice and people with cancer have high amounts of triglycerides as compared with DCs from tumor-free mice and healthy individuals.
Journal ArticleDOI
Upper-Airway Stimulation for Obstructive Sleep Apnea
Patrick J. Strollo,Ryan J. Soose,Joachim T. Maurer,Nico de Vries,Jason R. Cornelius,Oleg Froymovich,Ronald D. Hanson,Tapan A. Padhya,David L. Steward,M. Boyd Gillespie,Tucker Woodson,Paul Van de Heyning,Mark G. Goetting,Olivier M. Vanderveken,Neil T. Feldman,Lennart Knaack,Kingman P. Strohl +16 more
Journal ArticleDOI
Upper Airway Stimulation for Obstructive Sleep Apnea: 5-Year Outcomes.
B. Tucker Woodson,Kingman P. Strohl,Ryan J. Soose,M. Boyd Gillespie,Joachim T. Maurer,Nico de Vries,Nico de Vries,Tapan A. Padhya,M. Safwan Badr,Ho-Sheng Lin,Olivier M. Vanderveken,Sam Mickelson,Patrick J. Strollo +12 more
TL;DR: Improvements in sleepiness, quality of life, and respiratory outcomes are observed with 5 years of UAS, a nonanatomic surgical treatment with long-term benefit for individuals with moderate to severe OSA who have failed nasal continuous positive airway pressure.