T
Taylor M. Courtney
Researcher at University of Pittsburgh
Publications - 14
Citations - 555
Taylor M. Courtney is an academic researcher from University of Pittsburgh. The author has contributed to research in topics: Phosphatase & Kinase. The author has an hindex of 7, co-authored 11 publications receiving 380 citations.
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Optochemical Control of Biological Processes in Cells and Animals.
TL;DR: Recent developments of optochemical tools, including small molecules, peptides, proteins, and nucleic acids that can be irreversibly or reversibly controlled through light irradiation, are discussed, with a focus on applications in cells and animals.
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Recent advances in the optical control of protein function through genetic code expansion.
TL;DR: Using unnatural amino acids to generate light-triggered proteins enables a rational engineering approach that is based on mechanistic and/or structural information, including technological advances and biological applications.
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Optochemische Steuerung biologischer Vorgänge in Zellen und Tieren
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Enzyme Micropump‐Based Inhibitor Assays
TL;DR: Using this principle, sensors for toxic substances, like mercury, cadmium, cyanide, and azide, were designed using urease and catalase‐powered pumps, respectively, with limits of detection well below the concentrations permitted by the Environmental Protection Agency.
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Optical control of protein phosphatase function
TL;DR: A light-activated protein phosphatase is developed using photocaged, unnatural amino acids and used to study ERK nuclear translocation and it is discovered that ERKnuclear translocation is regulated in a graded manner in response to increasing MKP3 activity.