Teresa M. Coque

TL;DR: Genotyping revealed that nosocomial infections by multiresistant E. faecalis in Europe remains susceptible to ampicillin and glycopeptides, but the high prevalence of strains that are highly resistant to aminoglycosides excludes these antibiotics from combination therapies.

TL;DR: The fertility of the One Health approach to antibiotic resistance depends on the progress of understanding multihierarchical systems, encompassing communications among environments (macro/microaggregates), among microbiotas (communities), among bacterial species (clones), and communications among MGEs.

TL;DR: In this article, the authors study E. faecalis isolates ranging from the pre-antibiotic era in 1936 up to 2018, covering a large set of host species including wild birds, mammals, healthy humans, and hospitalised patients.

TL;DR: An emerging concept increasingly used in Public Health Microbiology and extensively treated in this Thematic Issue is reflected by the terms ‘high risk clones, or clonal complexes’, referring to highly specialized genetic populations or subpopulations with enhanced ability to colonize, spread and persist in particular niches after having acquired a diversity of adaptative traits.

TL;DR: The acquisition process of antibiotic resistance in an otherwise susceptible organism is shaped by the ecology of the species, and occasional increases in population sizes can derive from selection of thespecies based on intrinsic or acquired resistance to antibiotics, biocides, heavy metals or by a natural tolerance to extreme conditions.