T
Tessa J. J. de Bitter
Researcher at Radboud University Nijmegen
Publications - 19
Citations - 182
Tessa J. J. de Bitter is an academic researcher from Radboud University Nijmegen. The author has contributed to research in topics: Medicine & Gallbladder cancer. The author has an hindex of 6, co-authored 12 publications receiving 89 citations.
Papers
More filters
Journal ArticleDOI
Isocitrate dehydrogenase 1–mutated human gliomas depend on lactate and glutamate to alleviate metabolic stress
Krissie Lenting,Mohammed Khurshed,Tom H Peeters,Corina N. A. M. van den Heuvel,Sanne A. M. van Lith,Tessa J. J. de Bitter,Wiljan Hendriks,Paul N. Span,Remco J. Molenaar,Dennis Botman,Kiek Verrijp,Arend Heerschap,Mark ter Laan,Benno Küsters,Anne van Ewijk,Martijn A. Huynen,Cornelis J.F. Van Noorden,William P.J. Leenders +17 more
TL;DR: The data support an evolutionary model in which IDHmut glioma cells exist in symbiosis with supportive neuronal cells and astrocytes as suppliers of glutamate and lactate, possibly explaining the diffuse nature of these cancers.
Journal ArticleDOI
Re-resection in Incidental Gallbladder Cancer: Survival and the Incidence of Residual Disease
Elise A. J. de Savornin Lohman,Lydia G. M. van der Geest,Tessa J. J. de Bitter,Iris D. Nagtegaal,Cornelis J. H. M. van Laarhoven,Peter B. van den Boezem,Chella S. van der Post,Philip R. de Reuver +7 more
TL;DR: Re-resection for iGBC is associated with improved survival but remains infrequently used and is often performed after the optimal timing interval, and RD is the only significant prognostic factor for survival after re-resections and can be predicted by pT and pN stages.
Journal ArticleDOI
Trends in Treatment and Survival of Gallbladder Cancer in the Netherlands; Identifying Gaps and Opportunities from a Nation-Wide Cohort
Elise A. J. de Savornin Lohman,Tessa J. J. de Bitter,Rob H.A. Verhoeven,Lydia G. M. van der Geest,Jeroen Hagendoorn,Nadia Haj Mohammad,F. Daams,Heinz-Josef Klümpen,Thomas M. van Gulik,Joris I. Erdmann,Marieke T. de Boer,Frederik J H Hoogwater,Bas Groot Koerkamp,Andries E. Braat,Joanne Verheij,Iris D. Nagtegaal,Cornelis J. H. M. van Laarhoven,Peter B. van den Boezem,Rachel S. van der Post,Philip R. de Reuver +19 more
TL;DR: Radical surgery and palliative chemotherapy appear to improve prognosis but remain under-utilized in GBC, and survival of GBC remains poor.
Journal ArticleDOI
Molecular Profiling of Druggable Targets in Clear Cell Renal Cell Carcinoma Through Targeted RNA Sequencing.
Corina N. A. M. van den Heuvel,Anne van Ewijk,Carolien Zeelen,Tessa J. J. de Bitter,Martijn A. Huynen,Peter F.A. Mulders,Egbert Oosterwijk,William P.J. Leenders +7 more
TL;DR: Target RNA sequencing using single molecule Molecular Inversion Probes shows that t/RNA-NGS gene expression profiles can be used to predict in vitro sensitivity to targeted drugs, and may guide personalized therapy of renal cell cancers.
Journal ArticleDOI
Gallbladder Cancer: Current Insights in Genetic Alterations and Their Possible Therapeutic Implications.
Hendrien Kuipers,Tessa J. J. de Bitter,Marieke T. de Boer,Rachel S. van der Post,Maarten W Nijkamp,Philip R. de Reuver,Rudolf S N Fehrmann,Frederik J H Hoogwater +7 more
TL;DR: In this article, a literature search was performed utilizing PubMed, EMBASE, Cochrane Library, and Web of Science to provide an overview of frequently occurring genetic alterations occurring in gallbladder cancer and their possible therapeutic implications.