T
Tewis Bouwmeester
Researcher at Novartis
Publications - 100
Citations - 21203
Tewis Bouwmeester is an academic researcher from Novartis. The author has contributed to research in topics: Wnt signaling pathway & Gastrulation. The author has an hindex of 44, co-authored 99 publications receiving 19729 citations. Previous affiliations of Tewis Bouwmeester include European Bioinformatics Institute & Harvard University.
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Xenopus marginal coil (Xmc), a novel FGF inducible cytosolic coiled-coil protein regulating gastrulation movements.
TL;DR: The results suggest that Xmc is a novel FGF target gene that is required for morphogenetic movements during gastrulation in Xenopus, and Xmc loss-of-function does not interfere with mesoderm induction or maintenance per se.
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Absence of familiarity triggers hallmarks of autism in mouse model through aberrant tail-of-striatum and prelimbic cortex signaling
Sebastian Krüttner,A. M. Falasconi,Sergio Valbuena,Ivan Galimberti,Tewis Bouwmeester,Silvia Arber,Pico Caroni +6 more
TL;DR: This paper showed that exposure to novel environments lacking familiar features produces long-lasting failure to engage and repetitive behaviors upon re-exposure in Shank3-C/ΔC ASD model mice.
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Xwig1, a novel putative endoplasmic reticulum protein expressed during epithelial morphogenesis and in response to embryonic wounding.
TL;DR: Xwig1 provides a molecular link between epithelial morphogenesis and wound healing and is in part mediated by Elk-1, but independent of dissection-induced FGF signalling.
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New twists on embryonic patterning. EMBO workshop: embryonic organizer signaling: the next frontiers.
TL;DR: The complexity, mechanisms of action and the conceptual convergence/divergence of distinct embryonic organizer centers was discussed at the EMBO workshop on ‘Embryonic organizer signaling: the next frontiers’ held at theEMBL on April 28–30, 2001 in Heidelberg, and some of the salient themes that emerged are highlighted.
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Liver biopsy derived induced pluripotent stem cells provide unlimited supply for the generation of hepatocyte-like cells.
Diego Calabrese,Guglielmo Roma,Sebastian Bergling,Walter Carbone,Valentina Mele,Sandro Nuciforo,Isabel Fofana,Benedetta Campana,Dagmara Szkolnicka,David C. Hay,Jan S. Tchorz,Tewis Bouwmeester,Stefan Wieland,Markus H. Heim +13 more
TL;DR: PLCs and Li-iPSCs obtained from small pieces of human needle liver biopsies constitute a novel unlimited source for the production of HLCs, which retain a liver specific transcriptional footprint and can be propagated to provide an unlimited supply of cells for differentiation into Li-HLCs.