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Thierry Moreau

Researcher at François Rabelais University

Publications -  135
Citations -  4728

Thierry Moreau is an academic researcher from François Rabelais University. The author has contributed to research in topics: Proteases & Elafin. The author has an hindex of 37, co-authored 133 publications receiving 4392 citations. Previous affiliations of Thierry Moreau include Institut national de la recherche agronomique & National Institutes of Health.

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Journal ArticleDOI

Neutrophil elastase, proteinase 3 and cathepsin G : Physicochemical properties, activity and physiopathological functions

Brice Korkmaz, +2 more
- 01 Feb 2008 - 
TL;DR: The structural and functional properties of these proteases that may explain their specific biological roles, and facilitate their use as molecular targets for new therapeutic strategies are focused on.
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Is obesity an independent prognosis factor in woman breast cancer

Bilal Majed, +5 more
- 01 Sep 2008 - 
TL;DR: This survey confirms the prognosis role of obesity on one of the largest cohort by investigating several prognosis events and stresses that obesity prognosis effect was also related to breast cancer presentation at diagnosis time.
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Circadian rhythm in rest and activity: a biological correlate of quality of life and a predictor of survival in patients with metastatic colorectal cancer

Pasquale F. Innominato, +15 more
- 01 Jun 2009 - 
TL;DR: The associations between CircAct parameters, HRQoL, and survival, which were shown in this international study involving previously untreated metastatic colorectal cancer patients, confirm prior single-institution findings in mostly pretreated metastatic colon cancer patients.
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Multifaceted roles of human elafin and secretory leukocyte proteinase inhibitor (SLPI), two serine protease inhibitors of the chelonianin family.

Thierry Moreau, +5 more
- 01 Feb 2008 - 
TL;DR: This review focuses on recent findings revealing that SLPI and elafin/trappin-2 have many biological functions as diverse as anti-bacterial, anti-fungal, pro-viral,Anti-inflammatory and immuno-modulatory functions, in addition to their well-recognized role as protease inhibitors.
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Short and long-term effects on survival in breast cancer patients treated by primary chemotherapy: an updated analysis of a randomized trial.

Philippe Broët, +7 more
- 01 Nov 1999 - 
TL;DR: Investigating the potential short and long‐term benefits attributable to primary chemotherapy by applying weighted logrank tests suggested that primary chemotherapy delayed early death rates, without significantly modifying long-term event rates.