Showing papers by "Thomas Binz published in 2008"

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Journal Article•DOI•

Substrate recognition mechanism of VAMP/synaptobrevin-cleaving clostridial neurotoxins.

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Stefan Sikorra¹, Tina Henke¹, Thierry Galli², Thierry Galli³, Thomas Binz¹ - Show less +1 more•Institutions (3)

Hochschule Hannover¹, French Institute of Health and Medical Research², University of Paris³

25 Jul 2008-Journal of Biological Chemistry

TL;DR: The data show that, similar to the SNAP-25 proteolyzing BoNT/A and E, VAMP/synaptobrevin-specific clostridial neurotoxins also initiate substrate interaction, employing an exosite located N-terminal of the scissile peptide bond.

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64 citations