Thomas Boudou

TL;DR: Recent work on designing and controlling film properties at the nanometer and micrometer scales with a view to developing new biomaterial coatings, tissue engineered constructs that could mimic in vivo cellular microenvironments, and stem cell “niches” is highlighted.

TL;DR: Current mechanotransduction paradigms, along with the technologies that have shaped the field of mechanobiology, are discussed.

TL;DR: The potential for this approach to quantitatively demonstrate the impact of physical parameters on the maturation, structure, and function of cardiac tissue is highlighted and the suitability of this technique for high-throughput monitoring of drug-induced changes in spontaneous frequency or contractility in CMTs as well as high-speed imaging of calcium dynamics using fluorescent dyes is demonstrated.

TL;DR: In this paper, skeletal muscle myoblasts are genetically encoded to express a light-activated cation channel, Channelrhodopsin-2, which allows for spatiotemporal coordination of a multitude of skeletal myotubes that contract in response to pulsed blue light.

TL;DR: The use of polysaccharides as main film components, which stems from their intrinsic physical, chemical and biological properties, has been explored in many bio-applications, such as self-assembly of new kinds of mimics of extracellular matrices from plant and animal tissues.