There is large consent that successful training of deep networks requires many thousand annotated training samples. In this paper, we present a network and training strategy that relies on the strong use of data augmentation to use the available annotated samples more efficiently. The architecture consists of a contracting path to capture context and a symmetric expanding path that enables precise localization. We show that such a network can be trained end-to-end from very few images and outperforms the prior best method (a sliding-window convolutional network) on the ISBI challenge for segmentation of neuronal structures in electron microscopic stacks. Using the same network trained on transmitted light microscopy images (phase contrast and DIC) we won the ISBI cell tracking challenge 2015 in these categories by a large margin. Moreover, the network is fast. Segmentation of a 512x512 image takes less than a second on a recent GPU. The full implementation (based on Caffe) and the trained networks are available at http://lmb.informatik.uni-freiburg.de/people/ronneber/u-net .

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U-Net: Convolutional Networks for Biomedical Image Segmentation

We propose a deep convolutional neural network architecture codenamed Inception that achieves the new state of the art for classification and detection in the ImageNet Large-Scale Visual Recognition Challenge 2014 (ILSVRC14). The main hallmark of this architecture is the improved utilization of the computing resources inside the network. By a carefully crafted design, we increased the depth and width of the network while keeping the computational budget constant. To optimize quality, the architectural decisions were based on the Hebbian principle and the intuition of multi-scale processing. One particular incarnation used in our submission for ILSVRC14 is called GoogLeNet, a 22 layers deep network, the quality of which is assessed in the context of classification and detection.

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Going deeper with convolutions

Deep learning is a form of machine learning that enables computers to learn from experience and understand the world in terms of a hierarchy of concepts. Because the computer gathers knowledge from experience, there is no need for a human computer operator to formally specify all the knowledge that the computer needs. The hierarchy of concepts allows the computer to learn complicated concepts by building them out of simpler ones; a graph of these hierarchies would be many layers deep. This book introduces a broad range of topics in deep learning. The text offers mathematical and conceptual background, covering relevant concepts in linear algebra, probability theory and information theory, numerical computation, and machine learning. It describes deep learning techniques used by practitioners in industry, including deep feedforward networks, regularization, optimization algorithms, convolutional networks, sequence modeling, and practical methodology; and it surveys such applications as natural language processing, speech recognition, computer vision, online recommendation systems, bioinformatics, and videogames. Finally, the book offers research perspectives, covering such theoretical topics as linear factor models, autoencoders, representation learning, structured probabilistic models, Monte Carlo methods, the partition function, approximate inference, and deep generative models. Deep Learning can be used by undergraduate or graduate students planning careers in either industry or research, and by software engineers who want to begin using deep learning in their products or platforms. A website offers supplementary material for both readers and instructors.

Deep Learning

There is, I think, something ethereal about i —the square root of minus one. I remember first hearing about it at school. It seemed an odd beast at that time—an intruder hovering on the edge of reality.

Usually familiarity dulls this sense of the bizarre, but in the case of i it was the reverse: over the years the sense of its surreal nature intensified. It seemed that it was impossible to write mathematics that described the real world in …

I and i

We present a new dataset with the goal of advancing the state-of-the-art in object recognition by placing the question of object recognition in the context of the broader question of scene understanding. This is achieved by gathering images of complex everyday scenes containing common objects in their natural context. Objects are labeled using per-instance segmentations to aid in precise object localization. Our dataset contains photos of 91 objects types that would be easily recognizable by a 4 year old. With a total of 2.5 million labeled instances in 328k images, the creation of our dataset drew upon extensive crowd worker involvement via novel user interfaces for category detection, instance spotting and instance segmentation. We present a detailed statistical analysis of the dataset in comparison to PASCAL, ImageNet, and SUN. Finally, we provide baseline performance analysis for bounding box and segmentation detection results using a Deformable Parts Model.

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Microsoft COCO: Common Objects in Context

Inline quality rating of multi‐crystalline wafers based on photoluminescence images

Brain magnetic resonance imaging (MRI) in patients with Multiple Sclerosis (MS) shows regions of signal abnormalities, named plaques or lesions. The spatial lesion distribution plays a major role for MS diagnosis. In this paper we present a 3D MS-lesion segmentation method based on an adaptive geometric brain model. We model the topological properties of the lesions and brain tissues in order to constrain the lesion segmentation to the white matter. As a result, the method is independent of an MRI atlas. We tested our method on the MICCAI MS grand challenge proposed in 2008 and achieved competitive results. In addition, we used an in-house dataset of 15 MS patients, for which we achieved best results in most distances in comparison to atlas based methods. Besides classical segmentation distances, we motivate and formulate a new distance to evaluate the quality of the lesion segmentation, while being robust with respect to minor inconsistencies at the boundary level of the ground truth annotation.

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White Matter MS-Lesion Segmentation Using a Geometric Brain Model

We propose a unifying algorithm for non-smooth non-convex optimization. The algorithm approximates the objective function by a convex model function and finds an approximate (Bregman) proximal point of the convex model. This approximate minimizer of the model function yields a descent direction, along which the next iterate is found. Complemented with an Armijo-like line search strategy, we obtain a flexible algorithm for which we prove (subsequential) convergence to a stationary point under weak assumptions on the growth of the model function error. Special instances of the algorithm with a Euclidean distance function are, for example, Gradient Descent, Forward--Backward Splitting, ProxDescent, without the common requirement of a "Lipschitz continuous gradient". In addition, we consider a broad class of Bregman distance functions (generated by Legendre functions) replacing the Euclidean distance. The algorithm has a wide range of applications including many linear and non-linear inverse problems in signal/image processing and machine learning.

Non-smooth Non-convex Bregman Minimization: Unification and new Algorithms

In this paper, we investigate the problem of anticipating future dynamics, particularly the future location of other vehicles and pedestrians, in the view of a moving vehicle. We approach two fundamental challenges: (1) the partial visibility due to the egocentric view with a single RGB camera and considerable field-of-view change due to the egomotion of the vehicle; (2) the multimodality of the distribution of future states. In contrast to many previous works, we do not assume structural knowledge from maps. We rather estimate a reachability prior for certain classes of objects from the semantic map of the present image and propagate it into the future using the planned egomotion. Experiments show that the reachability prior combined with multi-hypotheses learning improves multimodal prediction of the future location of tracked objects and, for the first time, the emergence of new objects. We also demonstrate promising zero-shot transfer to unseen datasets.

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Multimodal Future Localization and Emergence Prediction for Objects in Egocentric View With a Reachability Prior

In one-class-learning tasks, only the normal case (foreground) can be modeled with data, whereas the variation of all possible anomalies is too erratic to be described by samples. Thus, due to the lack of representative data, the wide-spread discriminative approaches cannot cover such learning tasks, and rather generative models, which attempt to learn the input density of the foreground, are used. However, generative models suffer from a large input dimensionality (as in images) and are typically inefficient learners. We propose to learn the data distribution of the foreground more efficiently with a multi-hypotheses autoencoder. Moreover, the model is criticized by a discriminator, which prevents artificial data modes not supported by data, and enforces diversity across hypotheses. Our multiple-hypothesesbased anomaly detection framework allows the reliable identification of out-of-distribution samples. For anomaly detection on CIFAR-10, it yields up to 3.9% points improvement over previously reported results. On a real anomaly detection task, the approach reduces the error of the baseline models from 6.8% to 1.5%.

Thomas Brox

Papers

Inline quality rating of multi‐crystalline wafers based on photoluminescence images

White Matter MS-Lesion Segmentation Using a Geometric Brain Model

Non-smooth Non-convex Bregman Minimization: Unification and new Algorithms

Multimodal Future Localization and Emergence Prediction for Objects in Egocentric View With a Reachability Prior

Anomaly Detection With Multiple-Hypotheses Predictions