C
Cristina Granziera
Researcher at University Hospital of Basel
Publications - 160
Citations - 3987
Cristina Granziera is an academic researcher from University Hospital of Basel. The author has contributed to research in topics: Medicine & Multiple sclerosis. The author has an hindex of 26, co-authored 112 publications receiving 2874 citations. Previous affiliations of Cristina Granziera include University of Lausanne & École Polytechnique Fédérale de Lausanne.
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Journal ArticleDOI
Serum neurofilament as a predictor of disease worsening and brain and spinal cord atrophy in multiple sclerosis.
Christian Barro,Pascal Benkert,Giulio Disanto,Charidimos Tsagkas,Michael Amann,Yvonne Naegelin,David Leppert,Claudio Gobbi,Cristina Granziera,Özgür Yaldizli,Zuzanna Michalak,Jens Wuerfel,Ludwig Kappos,Katrin Parmar,Jens Kuhle +14 more
TL;DR: Serum neurofilament light chain levels are a real-time, easy to measure marker of neuro-axonal injury that is conceptually more comprehensive than brain MRI and correlated with concurrent and future clinical and MRI measures of disease activity and severity.
Journal ArticleDOI
Thickening in the somatosensory cortex of patients with migraine
Alexandre F. M. DaSilva,Cristina Granziera,Josh Snyder,Nouchine Hadjikhani,Nouchine Hadjikhani +4 more
TL;DR: The findings indicate the presence of interictal structural changes in the somatosensory cortex (SSC) of migraineurs, which is in line with diffusional abnormalities observed in the subcortical trigeminal somatoensory pathway of the same migraine cohort in a previous study.
Journal ArticleDOI
Anatomical Alterations of the Visual Motion Processing Network in Migraine with and without Aura
Cristina Granziera,Alexandre F. M. DaSilva,Josh Snyder,David S. Tuch,David S. Tuch,Nouchine Hadjikhani,Nouchine Hadjikhani +6 more
TL;DR: High-resolution cortical thickness measurement and diffusion tensor imaging revealed that migraineurs have alterations in superior colliculus and the lateral geniculate nucleus, which are also involved in visual processing, which could account for, or be the result of, the cortical hyperexcitability observed in migraineurs.
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Serum neurofilament light chain in early relapsing remitting MS is increased and correlates with CSF levels and with MRI measures of disease severity
Jens Kuhle,Christian Barro,Giulio Disanto,Amandine Mathias,Charlotte Soneson,Guillaume Bonnier,Özgür Yaldizli,Axel Regeniter,Tobias Derfuss,Mathieu Canales,Myriam Schluep,Renaud Du Pasquier,Gunnar Krueger,Cristina Granziera +13 more
TL;DR: CSF and serum NfL levels were highly correlated, and serum concentrations were increased in RRMS, which further support longitudinal studies of serum N fL as a potential biomarker of on-going disease progression and as a possible surrogate to quantify effects of neuroprotective drugs in clinical trials.
Journal ArticleDOI
Astrocyte-specific expression of aquaporin-9 in mouse brain is increased after transient focal cerebral ischemia.
Jérôme Badaut,Jérôme Badaut,Lorenz Hirt,Cristina Granziera,Julien Bogousslavsky,Pierre J. Magistretti,Pierre J. Magistretti,Luca Regli +7 more
TL;DR: The overexpression of AQP9 on astrocytes surrounding an ischemic lesion suggests that AQP 9 may also play a role in the regulation of postischemia edema and, in view of its permeability to monocarboxylates, in the clearance of lactate from the isChemic focus.