T
Thomas C. Sparks
Researcher at Dow AgroSciences
Publications - 172
Citations - 8853
Thomas C. Sparks is an academic researcher from Dow AgroSciences. The author has contributed to research in topics: Juvenile-hormone esterase & Permethrin. The author has an hindex of 44, co-authored 167 publications receiving 7464 citations. Previous affiliations of Thomas C. Sparks include University of California, Riverside & Louisiana State University.
Papers
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Journal ArticleDOI
IRAC: Mode of action classification and insecticide resistance management
Thomas C. Sparks,Ralf Nauen +1 more
TL;DR: Diversity is the spice of resistance management by chemical means and thus it provides an approach to IRM providing a straightforward means to identify potential rotation/alternation options.
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Spinosad – a case study: an example from a natural products discovery programme
TL;DR: The discovery and characterization of the soil actinomycete, Saccharopolyspora spinosa, and the insecticidal metabolite spinosad is presented as a case history of a successful project emerging from a natural products crop protection discovery programme.
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Discovery and characterization of sulfoxaflor, a novel insecticide targeting sap-feeding pests.
Yuanming Zhu,Michael R. Loso,Gerald B. Watson,Thomas C. Sparks,Richard B. Rogers,Jim X. Huang,B. Clifford Gerwick,Jonathan M. Babcock,Donald Kelley,Vidyadhar B. Hegde,Benjamin M. Nugent,James M. Renga,Ian Denholm,Kevin Gorman,Gerrit J. deBoer,James M. Hasler,Thomas J. Meade,James D. Thomas +17 more
TL;DR: Available data are consistent with sulfoxaflor acting via the insect nicotinic receptor in a complex manner, and reflect the unique structure of the sulfoximines compared with neonicotinoids.
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Natural products as insecticides: the biology, biochemistry and quantitative structure-activity relationships of spinosyns and spinosoids.
TL;DR: Artificial neural network-based quantitative structure activity relationship (QSAR) studies for the spinosyns suggested that modification of the 2',3',4'-tri-O-methylrhamnosyl moiety could improve activity and several spinosoids incorporating these modifications exhibited markedly improved lepidopteran activity compared to spinosad.
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A rapid assay for insect juvenile hormone esterase activity.
TL;DR: This is the first rapid assay proposed for isomerically pure, commercially available juvenile hormone I, and it is proposed that this assay is more rapid and less expensive than conventional chromatographic assays while yielding almost identical values of similar precision.