T
Thomas Delbeke
Researcher at Rega Institute for Medical Research
Publications - 6
Citations - 1287
Thomas Delbeke is an academic researcher from Rega Institute for Medical Research. The author has contributed to research in topics: Reassortment & Rotavirus. The author has an hindex of 5, co-authored 6 publications receiving 1199 citations.
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Journal ArticleDOI
Full Genome-Based Classification of Rotaviruses Reveals a Common Origin between Human Wa-Like and Porcine Rotavirus Strains and Human DS-1-Like and Bovine Rotavirus Strains
Jelle Matthijnssens,Max Ciarlet,Erica Heiman,Ingrid Arijs,Thomas Delbeke,Sarah M. McDonald,Enzo A. Palombo,Miren Iturriza-Gomara,Piet Maes,John T. Patton,Mustafizur Rahman,Mustafizur Rahman,Marc Van Ranst +12 more
TL;DR: The novel classification system allows the identification of (i) distinct genotypes, which probably followed separate evolutionary paths; (ii) interspecies transmissions and a plethora of reassortment events; and (iii) certain gene constellations that revealed a common origin between human Wa-like rotavirus strains and porcine rotav virus strains.
Journal ArticleDOI
Evolutionary History and Global Spread of the Emerging G12 Human Rotaviruses
Mustafizur Rahman,Mustafizur Rahman,Jelle Matthijnssens,Xuelei Yang,Thomas Delbeke,Ingrid Arijs,Koki Taniguchi,Miren Iturriza-Gomara,N Iftekharuddin,Tasnim Azim,Marc Van Ranst +10 more
TL;DR: The genetic analyses revealed that after introduction of the VP7 gene of the rare G12 genotype into more common local strains through reassortment, a vast genetic diversity was generated and several new variants with distinct gene constellations emerged.
Journal ArticleDOI
G8 Rotavirus Strains Isolated in the Democratic Republic of Congo Belong to the DS-1-Like Genogroup
Jelle Matthijnssens,Mustafizur Rahman,Mustafizur Rahman,Xuelei Yang,Thomas Delbeke,Ingrid Arijs,Jean-Pierre Kabue,Jean-Jacques Tamfum Muyembe,Marc Van Ranst +8 more
TL;DR: Genomic comparison of these two African G8 strains revealed that 10 out of their 11 gene segments, except for VP4, were nearly identical, suggesting that this rare G8P[8] rotavirus strain originated recently from a reassortment between a common G8p[6] strain and a strain with a P[8) specificity.
Full Genome-Based Classification of Rotaviruses Reveals Common Origin
Jelle Matthijnssens,Max Ciarlet,Erica Heiman,Ingrid Arijs,Thomas Delbeke,M Sarah,Enzo A. Palombo,Miren Iturriza-Gomara,Piet Maes,John T. Patton,Mustafizur,Marc Van Ranst +11 more
TL;DR: This poster presents a probabilistic procedure for quantifying the immune response to several types of viruses and its applications in clinical and epidemiological research.
Journal ArticleDOI
Sequence analysis and evolution of group B rotaviruses.
Mustafizur Rahman,Zahid Hassan,Hasan Zafrul,Farjana Saiada,Sukalyani Banik,Abu Syed Golam Faruque,Thomas Delbeke,Jelle Matthijnssens,Marc Van Ranst,Tasnim Azim +9 more
TL;DR: Phylogenetic analyses of the gene segments encoding the hemagglutinin (VP4), glycoprotein (VP7) and RNA-binding protein (NSP2) of group B rotaviruses showed that Bangladeshi strains were more similar to the Indian strains than to the prototype Chinese strains.