Showing papers in "Virus Research in 2007"

TL;DR: Current knowledge on the genomic variability, geographic distribution and zoonotic aspects of Hepevirus as well as the clinical significance of genotype and evolution of HEV are reviewed.

TL;DR: Hepatitis B virus has been evolving gradually over a long period of time, resulting in a large amount of genetic diversity, despite the constraints imposed by the complex genetic organization of the viral genome.

TL;DR: There appears to be a intricate ballet in exposing and hiding nuclear transport signals which leads to a unidirectional transport of the RNPs to the nucleus at the start of the infection process and an opposite unid Directional export of RNPs at the end of the infections.

TL;DR: It is suggested that SARS-CoV spike protein may play an important role in the pathogenesis of SARS, especially in inflammation and high fever.

TL;DR: Data indicate that SP70 represents a promising candidate for an effective synthetic peptide-based vaccine against EV71, and shows that the amino acid residues of SP70 are highly conserved amongst the VP1 sequences of EV71 strains from various sub-genogroups.

TL;DR: Avian reoviruses are highly resistant to interferon, and therefore they may be useful for investigating the mechanisms and strategies that viruses utilize to counteract the antiviral actions of interferons.

TL;DR: The genome sequences of three duck hepatitis virus type 1 (DHV-1) strains showed that they possessed a typical picornavirus genome organization apart from the unique possession of three in-tandem 2A genes, and phylogenetic and evolutionary analysis of DHv-1 reveals a new picornvirus clade.

TL;DR: Phylogenetic analysis of the 5'UTR, N(pro) and E2 coding regions showed this virus to be the most divergent pestivirus identified to date.

TL;DR: The results showed strong suppression of gene silencing activities for C4 and betaC1 but a weak activity for C2, further supporting their suppressor function.

TL;DR: Despite many unanswered questions, here it is document that quasispecies dynamics has provided an interpretation of the adaptability of the hepatitis viruses, with features conceptually similar to those observed with other RNA viruses, a reflection of the common underlying Darwinian principles.

TL;DR: Multiple genes are involved in virulence of Hong Kong H5N1 influenza A viruses for mice with the presence of lysine at aa627 in the PB2 gene exhibiting a significantly larger effect than the HA and NA genes.

TL;DR: HBx-mediated activation of these pathways of UPR probably promote HBV replication and expression in liver cells, and contribute to liver pathogenesis, and perhaps even to hepatocellular carcinoma (HCC) development.

TL;DR: It is proposed that these 17 isolates be classified as members of 13 new human enterovirus types, enteroviruses 79-88, 97, and 100-101, confirming that the 17 new strains belong to HEV-B.

TL;DR: The pathogenicity of circulating H5N1 HPAI viruses in ducks varies depending on the virus strain and the age of the duck and correlates with the level of viral replication in tissues.

TL;DR: The genome sequences of 90D and 04G revealed that both strains of the new serotype DHV (N-DHV) possessed a typical picornavirus genome organization apart from the unique possession of three in-tandem 2A genes present in DHV-1.

TL;DR: Hepatitis A virus (HAV), the causative agent of type A viral hepatitis, was first identified about three decades ago and possesses several characteristics that make it unique among the family Picornaviridae, particularly in terms of its mechanisms of polyprotein processing and virion morphogenesis.

TL;DR: Analysis of thin sections across enations induced by PVX expressing betaC1 shows the structure of the enation to be identical to those induced by CLCuD DNA beta in conjunction with a helper begomovirus.

TL;DR: This review will summarize the development and current state of molecular HCV clones and discuss the prospects and implications of the most recent achievements.

TL;DR: Oral administration of the crude and purified compound from the leaves of P. pinnata effectively inhibited WSSV pathogenesis and reduced the mortality of infected shrimp.

TL;DR: RCA proves to be a reliable technique allowing for the detection of new geminivirus species as it does not depend on the knowledge of specific primers, and will accelerate genomics studies of all viruses with small circular DNA genomes.

TL;DR: Results suggest that infected monocytes could serve as a reservoir for HCoV-229E, become activated, participate in the exacerbation of pulmonary pathologies, as well as serve as potential vectors for viral dissemination to host tissues, where it could be associated with other pathologies.

TL;DR: Results seem to indicate that detection of multiple HPV infection with HR-HPV types is not significantly better as a predictor of cervical cancer than single HR- HPV infection, though further longitudinal studies are needed to better clarify the relevance of these infections to the progression of cervical neoplasia.

TL;DR: The objective of this review is to summarize current knowledge regarding the various regulatory roles played by phosphorylation of nonstructural viral proteins in the replication of positive-strand RNA viruses.

TL;DR: By revisiting the genotypic diversity of HBV, an alternative explanation is that human HBV genotypes might have emerged by several zoonotic introductions, both in the Old and the New World.

TL;DR: It is confirmed that RSIV strain U-1 is more closely related to Korean RSIV isolates than previously thought, and the suppression of IE transcript may be responsible for the restricted replication in BF-2 cells.

TL;DR: Differences in the 5'UTR and polymerase with respect to more pathogenic genotypes that may explain its reduced neurovirulence are revealed.

TL;DR: It is demonstrated that the presence of a major alpha2,6 sialic acid on N-linked glycoproteins is not essential for human influenza virus infection in mice.

TL;DR: Porcine circovirus type 2 has been associated with several disease outcomes in swine, primarily postweaning multisystemic wasting syndrome (PMWS) and porcine dermatitis nephropathy syndrome (PDNS), and over an 8-year period (1999-2006), 36 PCV2 strains were detected.

TL;DR: The results imply that the attenuation mechanism of the Ni-CE strain is different from that of the RC-HL strain, thus suggesting that rabies virus can be attenuated by diverse mechanisms.

TL;DR: Study of infections with EV isolates from newly diagnosed T1D patients in human pancreatic islets revealed beta-cell tropism, and clearly affected the function of thebeta-cell, and caused a clear increase in the number of dead cells.