T
Thomas Fröhlich
Researcher at Ludwig Maximilian University of Munich
Publications - 140
Citations - 5294
Thomas Fröhlich is an academic researcher from Ludwig Maximilian University of Munich. The author has contributed to research in topics: Proteome & Medicine. The author has an hindex of 34, co-authored 120 publications receiving 4089 citations. Previous affiliations of Thomas Fröhlich include Center for Integrated Protein Science Munich.
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Journal ArticleDOI
Tailor-Made Protein Corona Formation on Polystyrene Microparticles and its Effect on Epithelial Cell Uptake.
Julia Jasinski,Magdalena V Wilde,Matthias Voelkl,Valérie Jérôme,Thomas Fröhlich,Ruth Freitag,Thomas Scheibel +6 more
TL;DR: Particle history has a significant impact on protein corona formation and subsequently on the interaction of particles with murine intestinal epithelial-like cells, however, as this study was limited to one cell type, further work is needed to assess if these observations can be generalized to other cell types.
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Betacellulin transgenic mice develop urothelial hyperplasia and show sex-dependent reduction in urinary major urinary protein content.
Helene Schulz,Helene Schulz,Maik Dahlhoff,Aleksandra Glogowska,Lin Zhang,Georg J. Arnold,Thomas Fröhlich,Marlon R. Schneider,Thomas Klonisch +8 more
TL;DR: Mass spectrometric analysis of urine revealed a significant down-regulation of major urinary proteins in female BTC transgenic mice, suggesting a novel role for systemic BTC in odor-based signaling in female transgenic BTC mice.
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The secretome of skin cancer cells activates the mTOR/MYC pathway in healthy keratinocytes and induces tumorigenic properties
Christine Hoesl,Enrica Zanuttigh,Thomas Fröhlich,Julia Philippou-Massier,Stefan Krebs,Helmut Blum,Maik Dahlhoff +6 more
TL;DR: The data demonstrate the impact of the secretome of cancer cells on the transcription machinery of the cells surrounding the tumor, leading to a tumorigenic cell fate.
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172 DOES ESTRADIOL-17β CAUSE CYCLE-DEPENDENT MODULATIONS OF UTERINE MILK PROTEIN IN BOVINE ENDOMETRIUM?
Susanne E. Ulbrich,K. Gross,Susanne E M Schmidt,Helmut Blum,R. Rottmayer,Stefan Hiendleder,Thomas Fröhlich,Guy Arnold,E. Wolf,Heinrich H. D. Meyer,Stefan Bauersachs +10 more
TL;DR: Bovine UTMP seems to play a decisive role for precise cyclic regulation of the bovine uterine milieu and during early embryo-maternal communication in pregnancy and the pre-implantation period.
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122 extensive alterations in the quantitative proteome profile during early embryonic development
TL;DR: This work generated a comprehensive qualitative proteomic dataset of bovine oocytes using a nano-LC-MS/MS approach on an Orbitrap XL mass spectrometer, and found which proteins in early embryonic stages are contributed by the maternal part of the embryo.