Georg J. Arnold

TL;DR: The Daphnia genome reveals a multitude of genes and shows adaptation through gene family expansions, and the coexpansion of gene families interacting within metabolic pathways suggests that the maintenance of duplicated genes is not random.

TL;DR: The study shows that CLP36 associates with actin filaments and stress fibers that are formed during shape change and spreading of platelets and during migration and contraction of endothelial cells, and suggests that this association might modulate the function of alpha-actinin-1.

TL;DR: A knockout mutation in the DEG15 gene of Arabidopsis prevents processing of the glyoxysomal malate dehydrogenase precursor to the mature form, and the GPP/Deg15 possesses specific characteristics and is therefore a new subgroup within the Deg proteases.

TL;DR: Proteins vulnerable to PMI were analyzed by the 2‐D DIGE analysis of cortex samples from three donors, and were derived from a variety of functional groups, including metabolic, structural, stress response, antioxidants, synaptosomal, and neuronal proteins.

TL;DR: In vitro data suggest that reagents directed against LRP/LR or LRP mRNA such as antibodies, polysulfated glycans, or small interfering RNAs, previously shown to encompass an anti-prion activity by blocking or downregulating the prion receptor L RP/LR, might also be potential cancer therapeutics blocking metastasis by interfering with the LRP-laminin interaction in neoplastic tissues.