T
Thomas H. Cauley
Researcher at Bio-Rad Laboratories
Publications - 6
Citations - 2255
Thomas H. Cauley is an academic researcher from Bio-Rad Laboratories. The author has contributed to research in topics: TaqMan & Digital polymerase chain reaction. The author has an hindex of 5, co-authored 6 publications receiving 1908 citations.
Papers
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Journal ArticleDOI
High-Throughput Droplet Digital PCR System for Absolute Quantitation of DNA Copy Number
Benjamin J. Hindson,Kevin D. Ness,Donald A. Masquelier,Phillip Belgrader,Nicholas J. Heredia,Anthony J. Makarewicz,Isaac J. Bright,Michael Y. Lucero,Amy L. Hiddessen,Tina C. Legler,Tyler K. Kitano,Michael R. Hodel,Jonathan Petersen,Paul Wyatt,Erin R. Steenblock,Pallavi Shah,Luc J. Bousse,Camille B. Troup,Jeffrey Clark Mellen,Dean K. Wittmann,Nicholas G. Erndt,Thomas H. Cauley,Ryan T. Koehler,Austin P. So,Simant Dube,Klint Rose,Luz Montesclaros,Shenglong Wang,David P. Stumbo,Shawn Hodges,Steven Romine,Fred P. Milanovich,Helen E. White,John F. Regan,George Karlin-Neumann,Christopher Hindson,Serge Saxonov,Bill W. Colston +37 more
TL;DR: A high-throughput droplet digital PCR system that enables processing of ∼2 million PCR reactions using conventional TaqMan assays with a 96-well plate workflow is described that will allow researchers to explore complex genetic landscapes, discover and validate new disease associations, and define a new era of molecular diagnostics.
Patent
Droplet generation system with features for sample positioning
TL;DR: In this article, a channel junction at which a stream of sample fluid is divided into droplets by a dividing flow of carrier fluid is defined, and features configured to position sample fluid for reduced contact between the sample fluid and one or more surface regions of the channel junction may improve the consistency of droplet formation.
Patent
System for detection of spaced droplets
TL;DR: In this paper, the authors present a system for spacing droplets from each other and for detection of spaced droplets, including methods and apparatus, for spacing and detection of droplets.
Patent
Method of making a droplet-generating device
TL;DR: In this paper, a first droplet-generating device may be produced, which may include a molded portion created at least in part with a mold, and also a plurality of droplet generators each formed by the molded portion.
Patent
Sample holder with a well having a wicking promoter
TL;DR: In this paper, a sample holding system, including methods and apparatus, including a holder defining a well having a wicking promoter that encourages flow of a sample to the bottom of the well, is described.