Thomas J. Gniadek

TL;DR: In participants with Covid-19, most of whom were unvaccinated, the administration of convalescent plasma within 9 days after the onset of symptoms reduced the risk of disease progression leading to hospitalization.

TL;DR: It is concluded that many cases of lung cancer could be inaccurately or variably scored for PD-L1 expression with a single biopsy sample, particularly when a threshold for the percentage of positive cells is used to determine eligibility for checkpoint blockade therapy.

TL;DR: It is shown that siRNA-mediated depletion of giantin resulted in more dispersed Golgi stacks after nocodazole treatment than by control treatment, without changing the average cisternal length, suggesting that the spatial organization of the Golgi ribbon is mediated by giantin, which also plays a role in cargo transport and sugar modifications.

TL;DR: High-titer CCP neutralizes SARS-CoV-2 variants despite no previous donor exposure to the variants, and antibody levels in the upper 10% as well as 100% of the post-delta COVID-19/post-vaccination units and the hyperimmunoglobulin effectively neutralized all three variants.

TL;DR: The evidence and rationale for recommendations for inpatient and outpatient treatment and prophylaxis of COVID-19 convalescent plasma are described.