L
Lise J Estcourt
Researcher at NHS Blood and Transplant
Publications - 178
Citations - 5529
Lise J Estcourt is an academic researcher from NHS Blood and Transplant. The author has contributed to research in topics: Platelet transfusion & Medicine. The author has an hindex of 30, co-authored 150 publications receiving 3732 citations. Previous affiliations of Lise J Estcourt include Royal Women's Hospital & University of Oxford.
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Journal ArticleDOI
Effect of Hydrocortisone on Mortality and Organ Support in Patients With Severe COVID-19: The REMAP-CAP COVID-19 Corticosteroid Domain Randomized Clinical Trial.
Derek C. Angus,Lennie P. G. Derde,Farah Al-Beidh,Djillali Annane,Yaseen M. Arabi,Abi Beane,Wilma van Bentum-Puijk,Lindsay R. Berry,Zahra Bhimani,Marc J. M. Bonten,Charlotte Bradbury,Frank M. Brunkhorst,Meredith Buxton,Adrian Buzgau,Allen C. Cheng,Menno de Jong,Michelle A. Detry,Lise J Estcourt,Lise J Estcourt,Mark Fitzgerald,Herman Goossens,Cameron Green,Rashan Haniffa,Alisa Higgins,Christopher M. Horvat,Sebastiaan J. Hullegie,Peter Kruger,Francois Lamontagne,Patrick R. Lawler,Kelsey Linstrum,Edward Litton,Elizabeth Lorenzi,John E. A. Marshall,John E. A. Marshall,Daniel F. McAuley,Anna McGlothin,Shay McGuinness,Shay McGuinness,Shay McGuinness,Bryan J. McVerry,Stephanie K. Montgomery,Paul R Mouncey,Srinivas Murthy,Alistair Nichol,Rachael Parke,Rachael Parke,Rachael Parke,Jane Parker,Kathryn M Rowan,Ashish Sanil,Marlene Santos,Christina Saunders,Christopher W. Seymour,Anne Turner,Frank L. van de Veerdonk,Balasubramanian Venkatesh,Balasubramanian Venkatesh,Ryan Zarychanski,Scott M. Berry,Roger J. Lewis,Roger J. Lewis,Colin McArthur,Steven A R Webb,Steven A R Webb,Steven A R Webb,Anthony C. Gordon +65 more
TL;DR: To determine whether hydrocortisone improves outcome for patients with severe COVID-19, an ongoing adaptive platform trial testing multiple interventions within multiple therapeutic domains, for example, antiviral agents, corticosteroids, or immunoglobulin was conducted.
Journal ArticleDOI
Guidelines for the Use of Platelet Transfusions
Lise J Estcourt,Janet Birchall,Shubha Allard,Stephen J Bassey,Peter Hersey,Jonathan P. Kerr,Andrew D Mumford,Simon J. Stanworth,Hazel Tinegate +8 more
TL;DR: This poster presents a state-of-the-art virtual reality simulation system that allows for real-time monitoring of the response of the immune system to treatments such as chemotherapy.
Journal ArticleDOI
A No-Prophylaxis Platelet-Transfusion Strategy for Hematologic Cancers
Simon J. Stanworth,Lise J Estcourt,Lise J Estcourt,Gillian Powter,Brennan C Kahan,C Dyer,Louise Choo,Lekha Bakrania,Charlotte Llewelyn,Timothy Littlewood,Richard Soutar,Derek Norfolk,Adrian Copplestone,Neil Smith,Paul Kerr,Gail Jones,Kavita Raj,David Westerman,Jeff Szer,N. Jackson,Peter G Bardy,Dianne Plews,Simon Lyons,Linley Bielby,Erica M. Wood,Michael F. Murphy,Michael F. Murphy,Topps Study Investigators +27 more
TL;DR: The results of this randomized, open-label, noninferiority trial support the need for the continued use of prophylaxis with platelet transfusion and show the benefit of such prophyllaxis for reducing bleeding, as compared with no prophYLaxis.
Journal ArticleDOI
Convalescent plasma or hyperimmune immunoglobulin for people with COVID-19: a living systematic review.
Vanessa Piechotta,Khai Li Chai,Sarah J Valk,Carolyn Doree,Ina Monsef,Erica M. Wood,Abigail Lamikanra,Catherine Kimber,Zoe McQuilten,Cynthia So-Osman,Lise J Estcourt,Nicole Skoetz +11 more
TL;DR: To continually assess, as more evidence becomes available, whether convalescent plasma or hyperimmune immunoglobulin transfusion is effective and safe in treatment of people with COVID-19, a first living update of this review is published.
Journal ArticleDOI
Platelet refractoriness--practical approaches and ongoing dilemmas in patient management.
TL;DR: This review will address a practical approach to the diagnosis and management of platelet refractoriness while highlighting on‐going dilemmas and knowledge gaps.