T
Thomas J. Learch
Researcher at Cedars-Sinai Medical Center
Publications - 24
Citations - 1020
Thomas J. Learch is an academic researcher from Cedars-Sinai Medical Center. The author has contributed to research in topics: Ankylosing spondylitis & Spondylitis. The author has an hindex of 12, co-authored 24 publications receiving 881 citations.
Papers
More filters
Journal ArticleDOI
The impact of tumor necrosis factor α inhibitors on radiographic progression in ankylosing spondylitis.
Nigil Haroon,Robert D. Inman,Thomas J. Learch,Michael H. Weisman,MinJae Lee,Mohammad H. Rahbar,Michael M. Ward,John D. Reveille,Lianne S. Gensler +8 more
TL;DR: Treatment with TNFα inhibitors appears to reduce radiographic progression in patients with ankylosing spondylitis, especially with early initiation and with longer duration of followup, and the protective effect of TNF α inhibitors was stronger after propensity score matching.
Journal ArticleDOI
Clinical and immunogenetic prognostic factors for radiographic severity in ankylosing spondylitis.
Michael M. Ward,Matthew Hendrey,James D. Malley,Thomas J. Learch,John C. Davis,John D. Reveille,Michael H. Weisman +6 more
TL;DR: The accuracy of the prognosis of radiographic severity in AS is improved by knowing the age at disease onset, sex, smoking history, and the presence of HLA-B*4100, DRB1*0804, DQA1*0401, DQB1*0603, DRb1*0801, and DPB1-0202 alleles.
Journal ArticleDOI
Ankylosing Spondylitis: Patterns of Radiographic Involvement—A Re-examination of Accepted Principles in a Cohort of 769 Patients
Jennifer H. Jang,Michael M. Ward,Adam N. Rucker,John D. Reveille,John C. Davis,John C. Davis,Michael H. Weisman,Thomas J. Learch +7 more
TL;DR: There were no sex differences in cervical-predominant involvement in ankylosing spondylitis and hip arthritis was strongly associated with worse spinal involvement.
Association study of genes related to bone formation and resorption and the extent of radiographic change in ankylosing spondylitis
Adrian Cortes,Walter P. Maksymowych,B P Wordsworth,Robert D. Inman,Patrick Danoy,Proton Rahman,M. A. Stone,Maripat Corr,Dafna D. Gladman,Ann W. Morgan,Helena Marzo-Ortega,M. M. Ward,Thomas J. Learch,John D. Reveille,Matthew A. Brown,M Weisman +15 more
TL;DR: In this article, a two-phase genotyping design was used to identify genetic associations with severity of radiographic damage in ankylosing spondylitis (AS).
Journal ArticleDOI
Association study of genes related to bone formation and resorption and the extent of radiographic change in ankylosing spondylitis
Adrian Cortes,Walter P. Maksymowych,B P Wordsworth,Robert D. Inman,Patrick Danoy,Proton Rahman,M. A. Stone,Maripat Corr,Lianne S. Gensler,Dafna D. Gladman,Ann W. Morgan,Helena Marzo-Ortega,M. M. Ward,Thomas J. Learch,John D. Reveille,Matthew A. Brown,Michael H. Weisman +16 more
TL;DR: Findings support roles for bone resorption and prostaglandins pathways in the osteoproliferative changes in ankylosing spondylitis.