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Thomas J. Webster
Researcher at Brown University
Publications - 48
Citations - 7932
Thomas J. Webster is an academic researcher from Brown University. The author has contributed to research in topics: PLGA & Bone regeneration. The author has an hindex of 30, co-authored 48 publications receiving 7569 citations. Previous affiliations of Thomas J. Webster include Purdue University & Rensselaer Polytechnic Institute.
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Enhanced functions of osteoblasts on nanophase ceramics
TL;DR: The results of the present study provided the first evidence of enhanced long-term (on the order of days to weeks) functions of osteoblasts cultured on nanophase ceramics, and clearly represent a unique and promising class of orthopaedic/dental implant formulations with improved osseointegrative properties.
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Specific proteins mediate enhanced osteoblast adhesion on nanophase ceramics
TL;DR: Select enhanced osteoblast adhesion was independent of surface chemistry and material phase but was dependent on the surface topography (specifically on grain and pore size) of nanophase ceramics.
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Osteoblast adhesion on nanophase ceramics
TL;DR: Evidence is provided of the ability of nanophase alumina and titania to simulate material characteristics of physiological bone that enhance protein interactions (such as adsorption, configuration, bioactivity, etc.) and subsequent osteoblast adhesion.
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Nanomedicine for implants: a review of studies and necessary experimental tools.
Huinan Liu,Thomas J. Webster +1 more
TL;DR: This review will first introduce the use of nanomaterials in a variety of implant applications highlighting their promise towards regenerating tissues, and cover currently available surface characterization techniques that emphasize nanoscale resolution pertinent for characterizing biological interactions with nanommaterials.
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Mechanisms of Enhanced Osteoblast Adhesion on Nanophase Alumina Involve Vitronectin
TL;DR: Results of the present study provided the first evidence of increased unfolding of vitronectin adsorbed on nanophase alumina, as well as dose-dependent inhibition of osteoblast adhesion on nanophone alumina pretreated with vitronECTin following preincubation.