T
Thomas L. Innerarity
Researcher at University of California, San Francisco
Publications - 140
Citations - 19796
Thomas L. Innerarity is an academic researcher from University of California, San Francisco. The author has contributed to research in topics: Apolipoprotein B & Lipoprotein. The author has an hindex of 74, co-authored 140 publications receiving 19461 citations. Previous affiliations of Thomas L. Innerarity include University of California, Berkeley & University of California.
Papers
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Journal ArticleDOI
Plasma lipoproteins: apolipoprotein structure and function.
TL;DR: Future studies will rely heavily on the use of recombinant DNA technology and site-specific mutagenesis to elucidate further the correlations between structure and function and the role of specific apolipoproteins in lipoprotein metabolism.
Journal ArticleDOI
Subendothelial retention of atherogenic lipoproteins in early atherosclerosis.
Kristina Skålén,Maria Gustafsson,Ellen Knutsen Rydberg,Lillemor Mattsson Hultén,Olov Wiklund,Thomas L. Innerarity,Jan Borén +6 more
TL;DR: Direct experimental evidence is presented that the atherogenicity of apoB-containing low-density lipoproteins (LDL) is linked to their affinity for artery wall proteoglycans and it is concluded that subendothelial retention of apOB100-containing lipoprotein is an early step in atherogenesis.
Journal ArticleDOI
Lipoprotein receptors and cholesterol homeostasis
Journal ArticleDOI
Abnormal lipoprotein receptor-binding activity of the human E apoprotein due to cysteine-arginine interchange at a single site.
Journal ArticleDOI
Complete protein sequence and identification of structural domains of human apolipoprotein B
Timothy J. Knott,Richard J. Pease,L. M. Powell,S. Wallis,Stanley C. Rall,Thomas L. Innerarity,B D Blackhart,W. H. Taylor,Yves L. Marcel,Ross W. Milne,David W. Johnson,M. Fuller,Aldons J. Lusis,Brian J. McCarthy,Robert W. Mahley,B. Levy-Wilson,James F. Scott +16 more
TL;DR: The complete 4,563-amino-acid sequence of apo B-100 precursor (relative molecular mass (Mr) 514,000 (514K)) determined from complementary DNA clones is reported, identifying a domain enriched in basic amino-acid residues as important for the cellular uptake of cholesterol by the LDL receptor pathway.