T
Thomas W. Wakefield
Researcher at University of Michigan
Publications - 407
Citations - 23278
Thomas W. Wakefield is an academic researcher from University of Michigan. The author has contributed to research in topics: Venous thrombosis & Thrombosis. The author has an hindex of 68, co-authored 395 publications receiving 20620 citations. Previous affiliations of Thomas W. Wakefield include Conrad Hotels & Scripps Research Institute.
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Journal ArticleDOI
Apixaban Versus Warfarin for Mechanical Heart Valve Thromboprophylaxis in a Swine Aortic Heterotopic Valve Model
Patrick A Lester,Dawn M. Coleman,Jose A. Diaz,Tatum Jackson,Angela E. Hawley,Angela R. Mathues,Brandon T. Grant,Robert M. Knabb,Eduardo Ramacciotti,Charles Frost,Yan Song,Thomas W. Wakefield,Daniel D. Myers +12 more
TL;DR: Apixaban is a promising candidate and may be a useful alternative to warfarin for thromboprophylaxis of mechanical heart valves, and no adverse bleeding events were observed in any apixaban groups.
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Do galectins play a role in venous thrombosis? a review.
TL;DR: The laboratory has recently identified galectin-3 binding protein (Gal-3BP) as being up-regulated in a microparticle proteomics analysis for deep venous thrombosis (DVT) patients compared to negative controls.
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Venous thrombosis epidemiology, pathophysiology, and anticoagulant therapies and trials in severe acute respiratory syndrome coronavirus 2 infection.
TL;DR: The overwhelming inflammatory response in patients with SARS-CoV-2 infection can lead to a hypercoagulable state, microthrombosis, large vessel thromBosis, and, ultimately, death.
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Role of selectins and fibrinolysis in VTE.
TL;DR: The role of selectins and fibrinolysis in the process of venous thrombogenesis is addressed and the role of stasis, changes in the vessel wall, and throm bogenicity in the blood is addressed.
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Severe Chronic Venous Insufficiency: Magnitude of the Problem and Consequences
Susan Tsai,Anna Dubovoy,Reid M. Wainess,Gilbert R. Upchurch,Thomas W. Wakefield,Peter K. Henke +5 more
TL;DR: Patients requiring hospitalization for severe chronic venous insufficiency at the local and national levels and to analyze factors related to primary amputation are characterized and the physiological and economic costs are significant and have not decreased over more than a decade.