Thomas W. Wakefield

TL;DR: In an age 65 and older subset of total patients who underwent radiofrequency ablation alone versus RFA + TIPP (transilluminated powered phlebectomy), there was a trend toward a higher percentage of patients who had RFA alone, and in this elderly subset, Venous Clinical Severity Scores tended to improve more with R FA alone compared to RFA+TIPP, without a significant difference in complications between the two procedures.

TL;DR: Thrombus size was decreased in the tPA-treated rats but not in those that received saline or plasmin, and levels of the prothrombotic marker plasma soluble P-selectin increased when pl asmin was administered, while thrombus structure and vein wall effects did not differ between groups.

TL;DR: The subcutaneous tissue pressure is significantly elevated in limbs with symptomatic varicose veins, and increases with disease severity, and the highest intramuscular tissue pressure was seen in obstructive venous disease, but was also significantly increased in C5-6 patients more importantly in the C 5-6 post-thrombotic limbs.

TL;DR: In this article , the histone methyltransferase Mixed Lineage Leukemia 1 (MLL1/KMT2A) is an important regulator of MO/Mφ expression of procoagulant and profibrinolytic factors such as tissue factor (F3; TF), urokinase (PLAU), and urogenase receptor (PLAUR) in non-infected and infected cells.