Thoraya A. Farghaly

TL;DR: The potency of these compounds as antimicrobial agents has been evaluated and results showed that derivatives which have di- and trithiazole rings displayed high activity that exceeds the used standard antibiotic.

TL;DR: Three series of novel pyrazole derivatives 2-6 were synthesized via two step procedure that utilizes hydrazonoyl chlorides 1a-d and enaminones 3a-D and 5 a-d, respectively as starting materials and revealed that the mechanism of action of the anti cancer activities of all the tested compounds is topoisomerase I inhibitor.

TL;DR: The ability of nine new synthesized compounds to inhibit Hepatitis C Virus and Subacute Sclerosing Panencephalitis (SSPE) due to structural similarity between ribavirin and some of the newly synthesised compounds were they contain triazoles and its bioisosters is demonstrated.

TL;DR: The antimicrobial activity for some selected products was screened, and the results obtained exploring the high potency of some of the tested compounds compared with the employed standard bactericides and fungicide.

TL;DR: The synthesis of thiazolyl chalcones and 4-hetarylthiazoles and the assertion of their structure are described and 3-(4-Methoxyphenyl)-1-(5-methyl-2-(methylamino)thiazol-4-yl)prop-2-en-1-one (chalcone derivative 3a) showed significant and broad antitumor activity that was more potent than Doxorubicin.