T
Tim C. Diss
Researcher at University College London
Publications - 52
Citations - 5565
Tim C. Diss is an academic researcher from University College London. The author has contributed to research in topics: Lymphoma & MALT lymphoma. The author has an hindex of 35, co-authored 52 publications receiving 5294 citations. Previous affiliations of Tim C. Diss include Guy's Hospital & University College Hospital.
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IDH1 and IDH2 mutations are frequent events in central chondrosarcoma and central and periosteal chondromas but not in other mesenchymal tumours
M Fernanda Amary,Krisztian Bacsi,Francesca Maggiani,Stephen Damato,Dina Halai,Fitim Berisha,Robin Pollock,Paul O'Donnell,Anita Grigoriadis,Tim C. Diss,Malihe Eskandarpour,Nadege Presneau,Pancras C.W. Hogendoorn,Andrew Futreal,Roberto Tirabosco,Adrienne M. Flanagan,Adrienne M. Flanagan +16 more
TL;DR: IDH1 and IDH2 mutations represent the first common genetic abnormalities to be identified in conventional central and periosteal cartilaginous tumours and speculate that a mosaic pattern of IDH‐mutation‐bearing cells explains the reports of diverse tumours (gliomas, AML, multiple cartILaginous neoplasms, haemangiomas) occurring in the same patient.
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Resistance of t(11;18) positive gastric mucosa-associated lymphoid tissue lymphoma to Helicobacter pylori eradication therapy
Hongxiang Liu,Agnes Ruskon-Fourmestraux,Anne Lavergne-Slove,Hongtao Ye,Thierry Jo Molina,Yoram Bouhnik,Rifat Hamoudi,Tim C. Diss,Ahmet Dogan,Francis Mégraud,Jean-Claude Rambaud,Ming-Qing Du,Peter G. Isaacson +12 more
TL;DR: Most H pylori-associated gastric MALT lymphomas that do not respond to antibiotic therapy are associated with t(11;18, q21;q21), which results in a chimeric transcript between the AP12 and MLT genes.
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High incidence of Kaposi sarcoma-associated herpesvirus-related non-Hodgkin lymphoma in patients with HIV infection and multicentric Castleman disease.
Eric Oksenhendler,Emmanuelle Boulanger,Lionel Galicier,Ming-Qing Du,Nicolas Dupin,Tim C. Diss,Rifat Hamoudi,Marie-Thérèse Daniel,Félix Agbalika,Chris Boshoff,Jean-Pierre Clauvel,Peter G. Isaacson,Véronique Meignin +12 more
TL;DR: Within a prospective cohort study on 60 HIV-infected patients with MCD, 14 patients developed KSHV/HHV8-associated non-Hodgkin lymphoma (NHL), which fell into 2 groups, suggesting different pathogenesis.
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Kaposi sarcoma–associated herpesvirus infects monotypic (IgMλ) but polyclonal naive B cells in Castleman disease and associated lymphoproliferative disorders
Ming-Qing Du,Hongxiang Liu,Tim C. Diss,Hongtao Ye,Rifat Hamoudi,Nicolas Dupin,Véronique Meignin,Eric Oksenhendler,Chris Boshoff,Peter G. Isaacson +9 more
TL;DR: KSHV infects monotypic but polyclonal naive B cells and is associated with a range of lymphoproliferative disorders frompolyclonal isolated plasmablasts and microlymphomas to monoclonal microlyymphoma and frank plasmblastic lymphomas in MCD patients.
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Neoplastic T cells in angioimmunoblastic T-cell lymphoma express CD10
Ayoma D. Attygalle,Rajai Al-Jehani,Tim C. Diss,P. Munson,Hongxiang Liu,Ming-Qing Du,Peter G. Isaacson,Ahmet Dogan +7 more
TL;DR: CD10 is a phenotypic marker that specifically identifies the tumor cells in 90% of AITL, including the early cases, and provides an objective criterion for accurate and early diagnosis of A ITL.