T
Ting Luo
Researcher at Sichuan University
Publications - 65
Citations - 2128
Ting Luo is an academic researcher from Sichuan University. The author has contributed to research in topics: Medicine & Breast cancer. The author has an hindex of 16, co-authored 29 publications receiving 1071 citations.
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Journal ArticleDOI
Trastuzumab Deruxtecan in Previously Treated HER2-Low Advanced Breast Cancer.
Shanu Modi,William Jacot,Toshinari Yamashita,Joohyuk Sohn,Maria Vidal,Eriko Tokunaga,Junji Tsurutani,Naoto Ueno,Aleix Prat,Yee Soo Chae,Keun Seok Lee,Naoki Niikura,Yeon Hee Park,Bing Xue,Xiao-juan Wang,Miguel Gil-Gil,Wei Liu,Jean-Yves Pierga,Seock-Ah Im,Halle C. F. Moore,Hope S. Rugo,Rinat Yerushalmi,Flora Zagouri,Andrea Gombos,Sung-Bae Kim,Qiang Liu,Ting Luo,Cristina Saura,Peter Schmid,Tao Sun,Dhiraj Gambhire,Lotus Yung,Yibin Wang,Jasmeet Singh,Patrik Vitazka,Gerold Meinhardt,Nadia Harbeck,David Cameron +37 more
TL;DR: In this phase 3 trial involving patients with HER2-low metastatic breast cancer, trastuzumab deruxtecan resulted in significantly longer progression-free and overall survival than the physician's choice of chemotherapy.
Journal ArticleDOI
Targeting mTOR for cancer therapy
TL;DR: Recent advances in exploring mTOR signaling and the development of mTOR inhibitors for cancer therapy are updated and the mechanisms underlying the resistance to mTOR inhibitor in cancer cells are discussed.
Journal ArticleDOI
Matrix metalloproteinases in tumorigenesis: an evolving paradigm.
TL;DR: The complex roles of MMPs and their endogenous inhibitors such as tissue inhibitors of metalloproteinase in tumorigenesis and strategies in suppressing M MPs are reviewed.
Journal ArticleDOI
Epigallocatechin gallate sensitizes breast cancer cells to paclitaxel in a murine model of breast carcinoma
Ting Luo,Jiao Wang,Yancun Yin,Hui-Ming Hua,Jing-jing Jing,Xiangming Sun,Minjing Li,You-You Zhang,Yangfu Jiang +8 more
TL;DR: In this paper, green tea polyphenol (-)-epigallocatechin gallate (EGCG) was used as a sensitizer to enhance the cytotoxicity of paclitaxel.
Journal ArticleDOI
mTORC2 promotes type I insulin-like growth factor receptor and insulin receptor activation through the tyrosine kinase activity of mTOR.
Yancun Yin,Hui Hua,Minjing Li,Shu Liu,Qingbin Kong,Ting Shao,Jiao Wang,Yuanming Luo,Qian Wang,Ting Luo,Yangfu Jiang +10 more
TL;DR: It is shown that mTOR possesses unexpected tyrosine kinase activity and activates IGF-IR/InsR, and this work identifies mTOR as a dual-specificity kinase and clarifies how mTORC2 promotes IGF-ir/ InsR activation.