Tomáš Urban

TL;DR: In this article, molecular changes underlying hypertrophic scarring following burns throughout all basic wound healing stages, i.e. during inflammation, proliferation and maturation, are reviewed. And different types of fibroblasts and their roles in skin repair and regeneration following burn injury are compared.

TL;DR: Whereas atrial myocardium contains less mitochondria than the ventricle, atrial bioenergetic profiles are comparable to left ventricles, and high resolution respirometry has been adapted to homogenates of fresh human cardiac muscle and shown to be reliable and reproducible.

TL;DR: Concentrations of propofol seen in plasma of sedated patients in ICU cause a significant inhibition of fatty acid oxidation in human skeletal muscle cells and reduce spare capacity of electron transfer chain in mitochondria.

TL;DR: In this article, the authors used Functional Electrical Stimulation-assisted Cycle ergometry (FESCE) to enable in-bed leg exercise independently of patients' volition and found that early use of FESCE-based progressive mobility program improves physical function in survivors of critical care after 6 months.

TL;DR: Unloaded FES cycling, but not volitional exercise causes significant lactate production without hypoxia in skeletal muscle, which can be significant in vulnerable patients’ groups.