T
Tomaso Zambelli
Researcher at ETH Zurich
Publications - 99
Citations - 2924
Tomaso Zambelli is an academic researcher from ETH Zurich. The author has contributed to research in topics: Polyelectrolyte & Nanopore. The author has an hindex of 28, co-authored 90 publications receiving 2152 citations.
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Journal ArticleDOI
Force-controlled manipulation of single cells: from AFM to FluidFM
Orane Guillaume-Gentil,Eva Potthoff,Dario Ossola,Clemens M. Franz,Tomaso Zambelli,Julia A. Vorholt +5 more
TL;DR: FluidFM combines AFM with microfluidics via microchanneled cantilevers with nano-sized apertures and demonstrates a broad spectrum of single-cell applications including isolation, deposition, adhesion and injection in a range of biological systems.
Journal ArticleDOI
Approaches to self-assembly of colloidal monolayers: A guide for nanotechnologists.
Valeria Lotito,Tomaso Zambelli +1 more
TL;DR: This review presents an extensive classification and comparison of the different techniques adopted for 2D self-assembly in order to provide useful guidelines for scientists approaching this field.
Journal ArticleDOI
Tunable Single-Cell Extraction for Molecular Analyses
Orane Guillaume-Gentil,Rashel V. Grindberg,Romain Kooger,Livie Dorwling-Carter,Vincent Martinez,Dario Ossola,Martin Pilhofer,Tomaso Zambelli,Julia A. Vorholt +8 more
TL;DR: This approach has uncovered the ability of cells to withstand extraction of up to several picoliters and opens opportunities to study cellular dynamics and cell-cell communication under physiological conditions at the single-cell level.
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Mechanical force induces mitochondrial fission
Sebastian Carsten Johannes Helle,Qian Feng,Mathias J. Aebersold,Luca Hirt,Raphael R Grüter,Afshin Vahid,Andrea Sirianni,Serge Mostowy,Jess G. Snedeker,Jess G. Snedeker,Anđela Šarić,Timon Idema,Tomaso Zambelli,Benoît Kornmann +13 more
TL;DR: It is proposed that MFF, owing to affinity for narrow mitochondria, acts as a membrane-bound force sensor to recruit the fission machinery to mechanically strained sites, and thus, mitochondria adapt to the environment by sensing and responding to biomechanical cues.
Journal ArticleDOI
Rapid and serial quantification of adhesion forces of yeast and Mammalian cells.
Eva Potthoff,Orane Guillaume-Gentil,Dario Ossola,Jérôme Polesel-Maris,Salomé LeibundGut-Landmann,Tomaso Zambelli,Julia A. Vorholt +6 more
TL;DR: Serial quantification of adhesion forces of different cell types using a single probe is established using fluidic force microscopy (FluidFM) to establish the basis for niche colonization and survival.