Tomiya Mano

TL;DR: Findings indicate that SP induced E‐cadherin expression through PKC and CaMK activation and suggest that a lack of SP may account in part for the pathogenesis of neurotrophic keratitis.

TL;DR: Thrombin may be a plasma-derived mitogen capable of stimulating retinal glial cells to proliferate when there is a breakdown of the blood-retinal barrier, and this finding suggests that a thorough wash-out of a thrombin-containing infusate and/or the rapid inactivation of this molecule would prevent Thrombin from exacerbating a proliferative disorder of the retina.

TL;DR: The findings demonstrated that the murine Sertoli line exhibits potent phagocytic function and suggest the regulation of this activity may differ from that in "professional" phagocytes, as well as suggesting thatphagocytosis by SERToli cells requires extracellular Ca++.

TL;DR: The results suggest that an endocrinological mediator is capable of inhibiting class II induction on resident endocrine tissue populations and, therefore, could help to diminish local CD4+ T-cell recognition of these cells.

TL;DR: Results show that IFN-gamma can regulate the expression of MHC molecules by human retina glial cells in culture, consistent with the concept that glia may play a role in immunological disorders affecting the retina.