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Carrie W. Rinker-Schaeffer
Researcher at University of Chicago
Publications - 83
Citations - 5044
Carrie W. Rinker-Schaeffer is an academic researcher from University of Chicago. The author has contributed to research in topics: Metastasis & Metastasis Suppressor Gene. The author has an hindex of 37, co-authored 83 publications receiving 4869 citations. Previous affiliations of Carrie W. Rinker-Schaeffer include Johns Hopkins University School of Medicine & Louisiana State University.
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Journal ArticleDOI
KAI1, a metastasis suppressor gene for prostate cancer on human chromosome 11p11.2.
Jin-Tang Dong,Patricia W. Lamb,Carrie W. Rinker-Schaeffer,Jasminka Vukanovic,Tomohiko Ichikawa,John T. Isaacs,J C Barrett +6 more
TL;DR: A gene from human chromosome 11p11.2 was isolated and was shown to suppress metastasis when introduced into rat AT6.1 prostate cancer cells.
Journal ArticleDOI
Metastasis-Suppressor Genes: A Review and Perspective on an Emerging Field
TL;DR: The evolving view of the mechanisms that regulate metastasis and the importance of metastasis-suppressor genes in this process are described and the potential for the identification of novel therapeutic targets is discussed.
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An orthotopic model of human osteosarcoma growth and spontaneous pulmonary metastasis.
Hue H. Luu,Quan Kang,Quan Kang,Jong Kyung Park,Jong Kyung Park,Weike Si,Weike Si,Qing Luo,Qing Luo,Wei Jiang,Hong Yin,Anthony G. Montag,Michael A. Simon,Terrance D. Peabody,Rex C. Haydon,Carrie W. Rinker-Schaeffer,Tong-Chuan He +16 more
TL;DR: In vitro characterization demonstrated that the 143B line had the greatest cell migration and the least cell adhesion activities among the three lines and should be a valuable tool to investigate factors that promote or inhibit osteosarcoma growth and/or metastasis.
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Metastasis Suppression: The Evolving Role of Metastasis Suppressor Genes for Regulating Cancer Cell Growth at the Secondary Site
Eric C. Kauffman,Victoria L. Robinson,Walter M. Stadler,Mitchell H. Sokoloff,Carrie W. Rinker-Schaeffer +4 more
TL;DR: Clinical assessment of metastasis suppressor gene product status in disseminated cancer cells may improve the accuracy of predicting the prognosis in patients with clinically localized disease and support growth at the secondary site as a clinical target for metastasis treatment and prevention.
Journal Article
Mitogen-activated Protein Kinase Kinase 4/Stress-activated Protein/Erk Kinase 1 (MKK4/SEK1), a Prostate Cancer Metastasis Suppressor Gene Encoded by Human Chromosome 17
Barbara A. Yoshida,Zita Dubauskas,Marina Chekmareva,Thomas R. Christiano,Walter M. Stadler,Carrie W. Rinker-Schaeffer +5 more
TL;DR: Chekmareva et al. as mentioned in this paper identified the mitogenactivated protein kinase kinase 4/stress-activated protein/Erk kinase 1 (MKK4/SEK1) gene as a candidate metastasis suppressor gene encoded by the approximately 70cM region.