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Tomokazu Shimazu

Researcher at Saitama Medical University

Publications -  22
Citations -  252

Tomokazu Shimazu is an academic researcher from Saitama Medical University. The author has contributed to research in topics: Nitric oxide & Pioglitazone. The author has an hindex of 8, co-authored 22 publications receiving 216 citations.

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Hyperphosphorylated tau deposition parallels prion protein burden in a case of Gerstmann-Sträussler-Scheinker syndrome P102L mutation complicated with dementia.

TL;DR: It is suggested that p-tau deposition in this GSS102 is secondarily induced by PrP but not by Aβ (secondary tauopathy), and it might be a more common phenomenon in long-standing GSS.
Journal Article

Aging of the autonomic nervous system

TL;DR: Data indicates that healthy aging is associated with elevated basal sympathetic nervous activity, and the reactivity of the sympathetic and the parasympathetic nervous activity are reduced with aging.
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Nitric oxide production during cerebral ischemia and reperfusion in eNOS- and nNOS-knockout mice.

TL;DR: In vivo data suggest that NO production in the striatum after reperfusion is closely related to activities of both nN OS and eNOS, and is mainly related to nNOS following reperfusions.
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Cerebral antioxidant enzyme increase associated with learning deficit in type 2 diabetes rats.

TL;DR: The results suggest that diabetes-induced brain impairment, which results in learning deficits, may have occurred before the appearance of the symptoms of overt diabetes.