T
Tomoya Fukui
Researcher at Kitasato University
Publications - 66
Citations - 1397
Tomoya Fukui is an academic researcher from Kitasato University. The author has contributed to research in topics: Lung cancer & Amrubicin. The author has an hindex of 16, co-authored 62 publications receiving 1197 citations. Previous affiliations of Tomoya Fukui include Cornell University.
Papers
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Journal ArticleDOI
EGFR Mutations Predict Survival Benefit From Gefitinib in Patients With Advanced Lung Adenocarcinoma: A Historical Comparison of Patients Treated Before and After Gefitinib Approval in Japan
Toshimi Takano,Tomoya Fukui,Yuichiro Ohe,Koji Tsuta,Seiichiro Yamamoto,Hiroshi Nokihara,Noboru Yamamoto,Ikuo Sekine,Hideo Kunitoh,Koh Furuta,Tomohide Tamura +10 more
TL;DR: EGFR mutations significantly predict both a survival benefit from gefitinib and a favorable prognosis in patients with advanced lung adenocarcinoma.
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Detection of EGFR mutations in archived cytologic specimens of non-small cell lung cancer using high-resolution melting analysis.
Kiyoaki Nomoto,Koji Tsuta,Toshimi Takano,Tomoya Fukui,Karin Yokozawa,Hiromi Sakamoto,Teruhiko Yoshida,Akiko Miyagi Maeshima,Tatsuhiro Shibata,Koh Furuta,Yuichiro Ohe,Yoshihiro Matsuno +11 more
TL;DR: HRMA of archived cytological specimens of advanced NSCLC is suggested to be useful for detecting EGFR mutations in clinical practice by establishing and validated an easy, inexpensive, and rapid method for detecting DEL and L858R from cytologic material by high-resolution melting analysis.
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Epidermal growth factor receptor mutation detection using high-resolution melting analysis predicts outcomes in patients with advanced non small cell lung cancer treated with gefitinib.
Toshimi Takano,Yuichiro Ohe,Koji Tsuta,Tomoya Fukui,Hiromi Sakamoto,Teruhiko Yoshida,Ukihide Tateishi,Hiroshi Nokihara,Noboru Yamamoto,Ikuo Sekine,Hideo Kunitoh,Yoshihiro Matsuno,Koh Furuta,Tomohide Tamura +13 more
TL;DR: High-resolution melting analysis is a precise method for detecting DEL and L858R mutations and is useful for predicting clinical outcomes in patients with advanced NSCLC treated with gefitinib.
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EGF shifts human airway basal cell fate toward a smoking-associated airway epithelial phenotype
Renat Shaykhiev,Wu-Lin Zuo,IonWa Chao,Tomoya Fukui,Bradley Witover,Angelika Brekman,Ronald G. Crystal +6 more
TL;DR: Analysis of the airway epithelium revealed that EGFR is enriched in airway BCs, whereas its ligand EGF is induced by smoking in ciliated cells, suggesting that activation of EGFR in airways BCs by smoking-induced EGF represents a unique mechanism whereby smoking can alter airwayhelial differentiation and barrier function.
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Epidermal growth factor receptor mutation status and clinicopathological features of combined small cell carcinoma with adenocarcinoma of the lung.
Tomoya Fukui,Koji Tsuta,Koh Furuta,Shun Ichi Watanabe,Hisao Asamura,Yuichiro Ohe,Akiko Miyagi Maeshima,Tatsuhiro Shibata,Noriyuki Masuda,Yoshihiro Matsuno +9 more
TL;DR: A patient with combined SCLC with Ad sharing an identical EGFR mutation in both the SCLS and Ad components is identified, providing useful information for better understanding the biology, natural history and clinical management of SCLCs.