T
Toshihiko Kubota
Researcher at University of Fukui
Publications - 139
Citations - 2808
Toshihiko Kubota is an academic researcher from University of Fukui. The author has contributed to research in topics: Magnetic resonance imaging & Glioma. The author has an hindex of 27, co-authored 139 publications receiving 2670 citations.
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Journal ArticleDOI
Production of matrix metalloproteinases and tissue inhibitor of metalloproteinases-1 by human brain tumors
Takao Nakagawa,Toshihiko Kubota,Masanori Kabuto,Kazufumi Sato,Hirokazu Kawano,Taro Hayakawa,Yasunori Okada +6 more
TL;DR: Findings suggest that MMP's play an important role in human brain tumor invasion, probably due to an imbalance between the production of M MP's and TIMP-1 by the tumor cells.
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A phase I/II clinical trial investigating the adverse and therapeutic effects of a postoperative autologous dendritic cell tumor vaccine in patients with malignant glioma
Chen Nen Chang,Yin Cheng Huang,Yin Cheng Huang,Den Mei Yang,Den Mei Yang,Ken-ichiro Kikuta,Kuo Jen Wei,Kuo Jen Wei,Toshihiko Kubota,Wen Kuang Yang,Wen Kuang Yang +10 more
TL;DR: It is concluded that autologous DC-tumor immunotherapy benefits patients with malignant glioma but may cause transient but reversible elevation of serum AST/ALT levels.
Journal Article
Perfusion Imaging of Meningioma by Using Continuous Arterial Spin-Labeling: Comparison with Dynamic Susceptibility-Weighted Contrast-Enhanced MR Images and Histopathologic Features
Hirohiko Kimura,H. Takeuchi,Yoshio Koshimoto,Hidetaka Arishima,Hidemasa Uematsu,Yasutaka Kawamura,Toshihiko Kubota,Harumi Itoh +7 more
TL;DR: CASL and T2DSC perfusion methods are comparable in the characterization of meningiomas and CASL is of use in assessing tumor microcirculation.
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Prognostic significance of microvessel density determined by an anti-CD105/endoglin monoclonal antibody in astrocytic tumors: comparison with an anti-CD31 monoclonal antibody.
TL;DR: It is suggested that anti‐CD105 mAb may be a better marker than anti-CD31 mAb in evaluation of angiogenesis and prediction of prognosis in astrocytic tumors.
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Central neurocytoma: immunohistochemical and ultrastructural study.
Toshihiko Kubota,M. Hayashi,H. Kawano,M. Kabuto,Kazufumi Sato,J. Ishise,K. Kawamoto,K. Shirataki,H. Iizuka,S. Tsunoda,J. Katsuyama +10 more
TL;DR: The most consistent finding for histological diagnosis was the presence of typical or abortive synapses with clear and dense-core vesicles in central neurocytomas, suggesting synaptophysin may be a specific marker for some central neuroCytomas.