Showing papers in "Journal of Clinical Neuroscience in 2011"

TL;DR: A pre-surgical evaluation should include a subclassification of FLE as dorsolateral frontal, mesial frontal or basal frontal lobe epilepsy to allow a minimal cortical resection, a review of the typical findings of seizure semiology, interictal and ictal EEG regarding the different FLE subtypes is given.

TL;DR: IL-17-secreting CD8(+)T cells were increased in patients with NMO and MS during relapse and have an important role in the pathological mechanism of N MO and MS.

TL;DR: In this paper, the authors discuss guidelines for safe implantation of percutaneous pedicle screws using an image intensifier technique and discuss potential indications for minimally invasive fusion techniques for complex spinal surgery and support these with descriptions of illustrative patients.

TL;DR: The results of studies completed thus far show that endovascular reconstruction with flow diverters is an effective treatment of wide-necked, fusiform, large, and giant unruptured intracranial aneurysms, with 5% to 10% of patients experiencing permanent major morbidity and mortality.

TL;DR: It is concluded that autologous DC-tumor immunotherapy benefits patients with malignant glioma but may cause transient but reversible elevation of serum AST/ALT levels.

TL;DR: Patients who underwent MIS TLIF had a statistically significant lower intraoperative transfusion rate, and rate of required postoperative surgical drains; and shorter periods of required drainage, and time to ambulation; however, the MISTLIF group tended to have a higher rate of complications, which might have been associated with the learning curve.

TL;DR: The findings suggest that nanoparticle silver ion-coated implants are as safe as uncoated titanium screws and that they can help prevent both biofilm formation and infection.

TL;DR: The included trials suggest that the treatment protocols of MS and SRS/SRT are of equal efficacy with regard to impact on QoL; however, the trials were hetereogenous and suffered from a variety of methodological deficiencies, so no meta-analysis was able to be performed.

TL;DR: Neuromelanin MRI may be considered as a biomarker of nigral degeneration in patients with PD and significantly reduced volumes for the left and right SNc were significantly reduced in Patients with PD compared to the controls.

TL;DR: The results indicate that intracapsular resection via the endoscopic approach can be a safe and effective treatment for giant pituitary adenomas.

TL;DR: The article will summarize indications and contraindications for SCS, provide guidance on the selection and timing for referral, and highlight the benefits and complications associated with the procedure.

TL;DR: The history, clinical presentation, physical examination findings, radiological images, and surgical and pathological records of 30 patients with SSEH treated between January 2002 and September 2010 have been reviewed and prognosis is discussed.

TL;DR: A higher prevalence of compromised posterior collaterals was observed in this Chinese population compared to Western and Japanese populations and is the first report of a CTA study of collateral circulation in a Chinese population.

TL;DR: It appears likely that the pathophysiology of freezing involves context-dependant dysfunction across multiple levels of the neurological system, including cortical, subcortical and brainstem regions.

TL;DR: Although anti-AQP4 antibodies appear to decrease overall following rituximab treatment, the findings raise concern over the potential for an early BAFF-mediated worsening of patients with NMO receiving ritUXimab.

TL;DR: While gross total resection of these tumors is the definitive treatment to prevent recurrence and aseptic meningitis, a subtotal resection may be necessary to preserve neurological function.

TL;DR: This case-based technical review outlines the SBRT apparatus, planning and treatment delivery in use at the University of Toronto, Toronto, Canada.

TL;DR: A male patient who underwent a fluorescein sodium-guided brain tumor excision and experienced an anaphylactic reaction with severe hypotension and bradycardia is presented, and physicians should be alerted to this rare but life-threatening adverse event.

TL;DR: A survey of the complete hemodynamic pathogenesis of aneurysmal SAH detailing the many factors and their connections that contribute to the pathophysiology of this disorder is presented.

TL;DR: The mechanisms of neural dysfunction in the acute porphyrias and the resultant clinical features of an acute attack are explored.

TL;DR: The single-center experience using detachable balloons, coils and Willis covered stents to treat post-traumatic direct carotid-cavernous fistulas (DCCFs) and the ICA was reviewed, finding 98% of DCCFs were successfully treated with the occlusion of the fistula and preservation of the I CA.

TL;DR: It is revealed that patients who lack the dystrophin isoform Dp140 have significantly greater cognitive problems, and the general intellectual abilities of a group of 25 boys with genetically confirmed Duchenne muscular dystrophy were evaluated.

TL;DR: A patient with optic nerve glioma treated at an institution is described and recent advances made in the diagnosis and treatment of these tumours over the past 10 years are reviewed.

TL;DR: Clinicians are suggested to consider including an EEG in the diagnostic procedures of patients under treatment with clarithromycin who develop features of neurotoxicity because an EEG can help to differentiate patients with psychiatric illness from those with encephalopathy or epilepsy.

TL;DR: A relatively young age of onset, with a high MGMT promoter methylation and PTEN protein expression were favorable factors for long-term survival, and the presence of EGFR amplification indicates that more than a single factor determines survival in GBM.

TL;DR: Patients with MS were found to have raised homocysteine levels but low B(12) levels, which might contribute to the pathogenesis of MS.

TL;DR: Brain ischemic postconditioning resulted in significantly increased GS expression compared with both the sham and ischemia-reperfusion groups, suggesting that upregulation of GS expression after ischemIA constitutes a neuroprotective mechanism.

TL;DR: A retrospective analysis of 309 patients who underwent surgical resection of newly diagnosed brain metastases revealed that patient age, performance status, extracranial metastases, complete resection, radiotherapy and re-craniotomy are independent factors of prolonged survival.

TL;DR: High definition spectral domain optical coherence tomography is a quick, inexpensive and promising tool to detect subclinical changes in RNFL and macular thickness in individuals with MS.

TL;DR: The potential role of PE as a rescue therapy in the management of steroid-unresponsive acute attacks of NMO, especially in patients with auto-antibodies against AQP-4 is highlighted.