T
Toshio Hattori
Researcher at Kumamoto University
Publications - 32
Citations - 1330
Toshio Hattori is an academic researcher from Kumamoto University. The author has contributed to research in topics: Antigen & Antibody. The author has an hindex of 17, co-authored 32 publications receiving 1310 citations. Previous affiliations of Toshio Hattori include Institute of Medical Science.
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Journal ArticleDOI
Characterization of a human immunodeficiency virus neutralizing monoclonal antibody and mapping of the neutralizing epitope
Shuzo Matsushita,Marjorie Robert-Guroff,J Rusche,Atsushi Koito,Toshio Hattori,H Hoshino,K Javaherian,Kiyoshi Takatsuki,S Putney +8 more
TL;DR: Results localize an epitope of HIV type-specific neutralization and suggest that neutralizing antibodies may be effective in controlling cell-associated, as well as cell-free, virus infection.
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Target epitope in the Tax protein of human T-cell leukemia virus type I recognized by class I major histocompatibility complex-restricted cytotoxic T cells.
Mari Kannagi,H Shida,H Igarashi,K Kuruma,H Murai,Yuko Aono,I Maruyama,Mitsuhiro Osame,Toshio Hattori,H Inoko +9 more
TL;DR: Tax-specific cytotoxicity, detected as cytolysis of the target cells infected with vaccinia virus-HTLV-I recombinant expressing Tax protein, was almost completely inhibited by competitor cells pulsed with the synthetic peptide, indicating that a major CTL epitope is present in this peptide.
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Preliminary evidence for inhibitory effect of glycyrrhizin on HIV replication in patients with AIDS.
Toshio Hattori,Shojiro Ikematsu,Atsushi Koito,Shuzo Matsushita,Yosuke Maeda,Masao Hada,Michio Fujimaki,Kiyoshi Takatsuki +7 more
TL;DR: It is suggested that GL might inhibit HIV-1 replication in vivo in hemophiliacs with acquired immune deficiency syndrome.
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Interference with human immunodeficiency virus (HIV) replication by CD8+ T cells in peripheral blood leukocytes of asymptomatic HIV carriers in vitro.
Mari Kannagi,Takao Masuda,Toshio Hattori,Tadashi Kanoh,Kaori Nasu,Naoki Yamamoto,Shinji Harada +6 more
TL;DR: It is demonstrated that peripheral blood leukocytes of asymptomatic HIV-1 carriers, following exogenous HIV- 1 infection in vitro, do not support viral replication, and observations suggest that certain populations of CD8+ lymphocyte-mediated interference with HIV replication could play an important role in the maintenance of the period of disease latency.
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Autocrine stimulation of interleukin 1 beta in acute myelogenous leukemia cells.
K Sakai,Toshio Hattori,Masao Matsuoka,Norio Asou,Seiko Yamamoto,Kimitaka Sagawa,Kiyoshi Takatsuki +6 more
TL;DR: Results indicated that autocrine secretion of IL-1 beta was involved in proliferation of some myelogenous leukemic cells.