M
Marjorie Robert-Guroff
Researcher at Kumamoto University
Publications - 7
Citations - 480
Marjorie Robert-Guroff is an academic researcher from Kumamoto University. The author has contributed to research in topics: Virus & Monoclonal antibody. The author has an hindex of 4, co-authored 7 publications receiving 478 citations.
Papers
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Journal ArticleDOI
Characterization of a human immunodeficiency virus neutralizing monoclonal antibody and mapping of the neutralizing epitope
Shuzo Matsushita,Marjorie Robert-Guroff,J Rusche,Atsushi Koito,Toshio Hattori,H Hoshino,K Javaherian,Kiyoshi Takatsuki,S Putney +8 more
TL;DR: Results localize an epitope of HIV type-specific neutralization and suggest that neutralizing antibodies may be effective in controlling cell-associated, as well as cell-free, virus infection.
Patent
A method for detecting HTLV-III neutralizing antibodies in sera
TL;DR: In this article, a method to measure natural human antibodies in sera which will neutralize HTLV-III infection in an in vitro assay was proposed, where cell-free virus is incubated with serum and used to infect H9 cells, which are then put in culture for three days, and viral infectivity is assayed using a monoclonal antibody specific for HTLV -III p24 in an immune fluorescent assay.
Journal ArticleDOI
Natural antibodies in sera from Japanese individuals infected with HTLV- I do not recognize HTLV-III
Toshio Hattori,Marjorie Robert-Guroff,Toru Chosa,Masao Matsuoka,Kazunari Yamaguchi,Toshinori Ishii,Robert C. Gallo,Kiyoshi Takatsuki +7 more
TL;DR: The data suggest that coincidental infection ofHTLV-I and HTLV-III is quite rare in Japan, and this area is a known endemic area for HTLV -I infection.
Journal ArticleDOI
Anti-HTLV-III and anti-HTLV-I antibodies and T cell subsets in hemophiliacs living in HTLV-I endemic and nonendemic areas of Japan.
Toshio Hattori,Shojiro Ikematsu,Toru Chosa,Seiko Yamamoto,Masao Matsuoka,Katsuhiro Fukutake,Marjorie Robert-Guroff,Kiyoshi Takatsuki +7 more
TL;DR: It was confirmed that hemophiliacs living in an HTLV-I endemic area and those living in a nonendemic area in Japan equally possessed antibodies to HT LVI, and low T4/T8 ratios and increases of serum IgG and IgM levels were found even in seronegative hemophiliaacs.
Book ChapterDOI
Immunology of human T-cell leukemia/lymphoma (lymphotropic) viruses (the HTLV ‘family’)
TL;DR: Under the broad scope provided by the title ‘immunology of HTLV’, the fairly extensive knowledge which has been acquired concerning these human retroviruses is reviewed and areas in which immunologic approaches have been especially useful in elucidating the nature of the virus and its interaction with environmental hosts are indicated.