T
Tsing-Bau Chen
Researcher at United States Military Academy
Publications - 70
Citations - 3873
Tsing-Bau Chen is an academic researcher from United States Military Academy. The author has contributed to research in topics: Angiotensin II & Angiotensin II receptor type 1. The author has an hindex of 24, co-authored 70 publications receiving 3676 citations. Previous affiliations of Tsing-Bau Chen include Merck & Co..
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Potent, orally active imidazo[4,5-b]pyridine-based angiotensin II receptor antagonists.
Nathan B. Mantlo,Prasun K. Chakravarty,Debra Ondeyka,Peter K. S. Siegl,R. S. L. Chang,Victor J. Lotti,Kristie A. Faust,Tsing-Bau Chen,Terry W. Schorn,Charles S. Sweet +9 more
Journal Article
Characterization of the binding of [3H]-(+/-)-L-364,718: a new potent, nonpeptide cholecystokinin antagonist radioligand selective for peripheral receptors.
TL;DR: Data indicate that [3H]-(+/-)-L-364,718 represents a new potent nonpeptide antagonist radioligand for the study of peripheral CCK receptors which may allow differentiation of agonist and antagonist interactions.
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Neuropeptide Y (NPY) binding sites in rat brain labeled with 125I-Bolton-Hunter NPY: comparative potencies of various polypeptides on brain NPY binding and biological responses in the rat vas deferens.
TL;DR: The rank order of potencies for NPY analogs and the inactivity of APP and HPP fragment on brain binding appeared to correlate with their relative activities in inhibiting contractions of the field-stimulated rat vas deferens, however, PYY, HPP and RPP exhibited activity in the fields indicative of a possible action upon sites distinct from the brain NPY binding site.
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A potent, orally active, balanced affinity angiotensin II AT1 antagonist and AT2 binding inhibitor.
S. E. De Laszlo,Carol S. Quagliato,William J. Greenlee,A A Patchett,R. S. L. Chang,Victor J. Lotti,Tsing-Bau Chen,S A Scheck,Kristie A. Faust,S S Kivlighn +9 more
Journal Article
Characterization of the binding of [3H]L-365,260: a new potent and selective brain cholecystokinin (CCK-B) and gastrin receptor antagonist radioligand.
Raymond S.L. Chang,Tsing-Bau Chen,Mark G. Bock,Roger M. Freidinger,R. Chen,A. Rosegay,V. J. Lotti +6 more
TL;DR: The data indicates that [3H]L-365,260 represents a new potent nonpeptide antagonist radioligand suitable for the study of brain CCK-B and gastrin receptors.