T
Tsuyoshi Tanaka
Researcher at Tokyo University of Agriculture and Technology
Publications - 193
Citations - 5579
Tsuyoshi Tanaka is an academic researcher from Tokyo University of Agriculture and Technology. The author has contributed to research in topics: Diatom & Circulating tumor cell. The author has an hindex of 37, co-authored 179 publications receiving 4910 citations. Previous affiliations of Tsuyoshi Tanaka include Heriot-Watt University & University of Tokyo.
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Journal ArticleDOI
Size-Selective Microcavity Array for Rapid and Efficient Detection of Circulating Tumor Cells
Masahito Hosokawa,Taishi Hayata,Yorikane Fukuda,Atsushi Arakaki,Tomoko Yoshino,Tsuyoshi Tanaka,Tadashi Matsunaga +6 more
TL;DR: A microfluidic device equipped with a size-selective microcavity array for highly efficient and rapid detection of tumor cells from whole blood was developed and can be used to study CTCs in detail.
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Controlled formation of magnetite crystal by partial oxidation of ferrous hydroxide in the presence of recombinant magnetotactic bacterial protein Mms6.
TL;DR: Protein quantification analysis of Mms6 in the synthesised particles indicated tight association of this protein onto the crystal, suggesting that the protein acts as a template for the nucleus formation and/or acts as an growth regulator by recognising crystal faces.
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Fully automated chemiluminescence immunoassay of insulin using antibody-protein A-bacterial magnetic particle complexes.
TL;DR: The fully automated sandwich immunoassay system using antibody-protein A-BMP complexes made possible precise assays of human insulin in serum and luminescence intensity from antibody- protein A-bacterial magnetic particle (BMP) complexes after immunoreaction was higher than that from BMPs chemically conjugated to an antibody.
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Fabrication of amino silane-coated microchip for DNA extraction from whole blood.
Takahito Nakagawa,Tsuyoshi Tanaka,Daisuke Niwa,Tetsuya Osaka,Haruko Takeyama,Tadashi Matsunaga +5 more
TL;DR: Determination of the number of surface amine groups and optimization of DNA capture condition were demonstrated and performance of PCR for the eluted fraction indicates that DNA extracted from whole blood was well purified using amine-coated microchip.
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Size-Based Isolation of Circulating Tumor Cells in Lung Cancer Patients Using a Microcavity Array System
Masahito Hosokawa,Hirotsugu Kenmotsu,Yasuhiro Koh,Tomoko Yoshino,Takayuki Yoshikawa,Tateaki Naito,Toshiaki Takahashi,Haruyasu Murakami,Yukiko Nakamura,Asuka Tsuya,Takehito Shukuya,Akira Ono,Hiroaki Akamatsu,Reiko Watanabe,Sachiyo Ono,Keita Mori,Hisashige Kanbara,Ken Yamaguchi,Tsuyoshi Tanaka,Tadashi Matsunaga,Nobuyuki Yamamoto +20 more
TL;DR: The MCA system has a potential to isolate significantly more CTCs and CTC clusters in advanced lung cancer patients compared to the CellSearch system, which employs the conventional EpCAM-based method.