Tuan Hoang

TL;DR: In vivo electrical functionality of the Parylene C-based 3D probes and their suitability for recording the neuronal activity over a 28-day period was demonstrated by maintaining the 1 kHz electrical impedance within a functional range and achieving a reasonably high signal-to-noise ratio for detection of resolvable multi-unit neuronal activity on most recording sites in the probe.

TL;DR: Quantitative 1-hydrogen MRS and decoupled 31-phosphorus MRS are sensitive to ±10% alterations in key cerebral metabolites, and may be of value in noninvasive monitoring of appropriate therapies, but previously described failure of global energy metabolism in HD was not confirmed.

TL;DR: A Parylene C neural probe with a three dimensional sheath structure that will enhance tissue integration and improve recording quality towards realizing reliable chronic neural interfaces was developed and successfully demonstrated in vitro into an agarose brain tissue model.

TL;DR: It is suggested that p-AsA is more mobile than methylated and inorganic forms of arsenic and that the transport of nanoparticles with p- asA(ads) might play a role in its mobility in geochemical environments.

TL;DR: Investigation of MEMS actuators, valves, and other microstructures for on-demand dosing control may enable next generation implantable pumps with high performance within a miniaturized form factor for clinical applications.