T
Tuo Yang
Researcher at University of Pittsburgh
Publications - 24
Citations - 1453
Tuo Yang is an academic researcher from University of Pittsburgh. The author has contributed to research in topics: Neuroprotection & Medicine. The author has an hindex of 12, co-authored 19 publications receiving 852 citations.
Papers
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Journal ArticleDOI
Blood-brain barrier dysfunction and recovery after ischemic stroke.
Xiaoyan Jiang,Xiaoyan Jiang,Anuska V. Andjelkovic,Ling Zhu,Tuo Yang,Michael V. L. Bennett,Michael V. L. Bennett,Jun Chen,Jun Chen,Richard F. Keep,Yejie Shi +10 more
TL;DR: With the development of novel research tools, future research on theBBB is likely to reveal promising potential therapeutic targets for protecting the BBB and improving patient outcome after ischemic stroke.
Journal ArticleDOI
Lymphatic drainage system of the brain: A novel target for intervention of neurological diseases
Bao-liang Sun,Li-hua Wang,Tuo Yang,Jing-yi Sun,Leilei Mao,Ming-feng Yang,Hui Yuan,Robert A. Colvin,Xiao-yi Yang +8 more
TL;DR: The clinical importance of ependymal route-based targeted gene therapy and intranasal drug administration in the brain by taking advantage of the unique role played by brain lymphatic pathways in the regulation of CSF flow and ISF/CSF exchange is highlighted.
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Peroxisome proliferator-activated receptor γ (PPARγ): A master gatekeeper in CNS injury and repair.
Wei Cai,Tuo Yang,Huan Liu,Lijuan Han,Kai Zhang,Xiaoming Hu,Xuejing Zhang,Ke-Jie Yin,Yanqin Gao,Michael V. L. Bennett,Rehana K. Leak,Jun Chen,Jun Chen,Jun Chen +13 more
TL;DR: The therapeutic potential of PPARγ in stroke and brain trauma is reviewed and the novel role of PParγ in long-term tissue repair is highlighted, which lies at the apex of cell fate decisions and exerts profound effects on the chronic progression of acute injury conditions.
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Impact of microRNAs on ischemic stroke: From pre- to post-disease.
Guangwen Li,Kahlilia C Morris-Blanco,Mary S. Lopez,Tuo Yang,Haiping Zhao,Raghu Vemuganti,Yumin Luo +6 more
TL;DR: This review lists miRNAs that have been reported to regulate various stroke risk factors and pre-disease mechanisms, including hypertension, atherosclerosis, and diabetes, followed by an in-depth analysis of mi RNAs in ischemic stroke pathogenesis, such as excitotoxicity, oxidative stress, inflammation, apoptosis, angiogenesis and neurogenesis.
Journal ArticleDOI
The impact of cerebrovascular aging on vascular cognitive impairment and dementia.
TL;DR: A review of recent findings on VCID is summarized, with a focus on vascular age-related pathologies and their contribution to the development of this condition.