Tyler B. Rice

TL;DR: The results show that SFDI is capable of revealing quantitative functional contrast in an AD model and may be a useful method for studying dynamic alterations in AD neural tissue composition and physiology.

TL;DR: The study demonstrates the feasibility of SFDI for providing enhanced image guidance during surgical resection of brain tumors by recovering absorption, scattering, and fluorescence properties of glioblastoma multiforme spheroids in tissue-simulating phantoms and in vivo in a mouse model.

TL;DR: LSI is integrated with spatial frequency domain imaging (SFDI) to suppress multiple scattering and absorption effects and provides an integrated approach for simultaneous mapping of blood flow and oxygenation and optical properties which can be used to inform tissue metabolism.

TL;DR: The feasibility of spatial frequency domain imaging (SFDI) for breast surgical margin assessment was evaluated in tissue-simulating phantoms and in fully intact lumpectomy specimens at the time of surgery to potentially reduce the high secondary excision rate associated with breast conserving surgery.

TL;DR: The results demonstrate the potential of FLaME to perform tissue optical property mapping in visible spectral regions and highlight how the optical clearing effect of saline is correlated to a decrease in μs′ of the skull.