U
Ulku Guler
Researcher at Hacettepe University
Publications - 7
Citations - 138
Ulku Guler is an academic researcher from Hacettepe University. The author has contributed to research in topics: Aptamer & Phosphopeptide. The author has an hindex of 5, co-authored 7 publications receiving 100 citations.
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Journal ArticleDOI
Design of an aptamer-based magnetic adsorbent and biosensor systems for selective and sensitive separation and detection of thrombin
TL;DR: The selectivity of the aptasensor system was tested with three different proteins and showed high specificity to thrombin and was regenerated by washing with NaOH solution, and repeatedly used until 20 cycles without a change in the performance.
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Lysozyme specific aptamer immobilized MCM-41 silicate for single-step purification and quartz crystal microbalance (QCM)-based determination of lysozyme from chicken egg white
TL;DR: The reusability studies showed that, about 87% of the initial adsorption capacity of the aptamer immobilized particles could be maintained after 20 cycles of purification, and the specific interaction between lysozyme specific aptamer sequences and Lysozyme was investigated by quartz crystal microbalance biosensor for determination of lyso enzyme in the egg samples.
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Human Gut Commensal Membrane Vesicles Modulate Inflammation by Generating M2-like Macrophages and Myeloid-Derived Suppressor Cells.
Esin Alpdundar Bulut,Banu Bayyurt Kocabas,Volkan Yazar,Gamze Aykut,Ulku Guler,Bekir Salih,Naz Surucu Yilmaz,Ihsan Cihan Ayanoglu,Muammer Merve Polat,Kamil Can Akcali,Ihsan Gursel,Mayda Gursel +11 more
TL;DR: It is shown that MVs isolated from the human lactic acid commensal bacteria Pediococcus pentosaceus suppressed Ag-specific humoral and cellular responses and hold promise as therapeutic agents in management/treatment of inflammatory conditions.
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A novel tantalum-based sol-gel packed microextraction syringe for highly specific enrichment of phosphopeptides in MALDI-MS applications.
TL;DR: The phosphopeptide enrichment performance of the tantalum-based sol-gels was found to be remarkably higher than the more crystalline Ta2O5 in the authors' studies.
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A Trypsin Immobilized Sol-Gel for Protein Indentification in MALDI-MS Applications
TL;DR: The trypsin immobilized sol-gel showed superior enzymatic activity in protein digestion and it was determined that thesol-gel material could be repeatedly used at least 25 times without significant activity loss in long-term use.