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Ulrich Vogel

Researcher at University of Würzburg

Publications -  185
Citations -  8661

Ulrich Vogel is an academic researcher from University of Würzburg. The author has contributed to research in topics: Neisseria meningitidis & Vaccination. The author has an hindex of 43, co-authored 174 publications receiving 7800 citations. Previous affiliations of Ulrich Vogel include Carlos III Health Institute.

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The role of patients and healthcare workers Staphylococcus aureus nasal colonization in occurrence of surgical site infection among patients admitted in two centers in Tanzania.

TL;DR: The finding of more than 90% of S. aureus SSI to be of endogenous source underscores the need of improving infection prevention and control measures including screening and decolonization of high risk patients.
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Immunogenicity of meningococcus C vaccination in a patient with atypical hemolytic uremic syndrome (aHUS) on eculizumab therapy.

TL;DR: Investigation of the immunogenicity of meningococcus C vaccination in a patient with atypical hemolytic uremic syndrome (aHUS) on eculizumab therapy concludes that the vaccine protects against meningitis C.
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Failure of first meningococcal vaccination in patients with atypical haemolytic uraemic syndrome treated with eculizumab.

TL;DR: Immunogenicity of first quadrivalent meninongococcal vaccination is insufficient in patients with atypical haemolytic uraemic syndrome and establishing antibiotic prophylaxes seems pivotal.
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Deletion of the Meningococcal fetA Gene Used for Antigen Sequence Typing of Invasive and Commensal Isolates from Germany: Frequencies and Mechanisms

TL;DR: Among invasive meningococcal isolates from 2,201 patients in Germany, 11 strains were identified lacking the fetA gene because of deletions mediated by repeat arrays flanking the gene, i.e., Correia elements, repeat sequence 13 (RS13), and duplicated RS3.
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Opc expression, LPS immunotype switch and pilin conversion contribute to serum resistance of unencapsulated meningococci.

TL;DR: The study highlights the ability of meningococci to adapt to environmental stress by phase variation and intrachromosomal recombination affecting subcapsular antigens and suggests that autoaggregation reduced the surface area accessible to serum complement and protected from killing.