Ulrike Nienaber

TL;DR: ROTEM®-guided haemostatic therapy, with fibrinogen concentrate as first-line haemOSTatic therapy and additional PCC, was goal-directed and fast, and a favourable survival rate was observed.

TL;DR: TEM-guided haemostatic therapy with fibrinogen concentrate and PCC reduced the exposure of trauma patients to allogeneic blood products.

TL;DR: F IBTEM A10 and FIBTEM MCF provided similar predictive values for massive transfusion in trauma patients to the most predictive laboratory parameters, and the best predictive values were provided by hemoglobin and Quick value.

TL;DR: SI upon emergency department arrival may be considered a clinical indicator of hypovolemic shock in respect to transfusion requirements, hemostatic resuscitation and mortality and the four SI groups have been shown to equal the recently suggested BD-based classification.

TL;DR: The updated RISC II prognostic score has several advantages over the previous RISC model, and discrimination, precision and calibration are improved, and patients with partial missing values could now be included.