U
Umberto D'Alessandro
Researcher at University of London
Publications - 289
Citations - 13619
Umberto D'Alessandro is an academic researcher from University of London. The author has contributed to research in topics: Malaria & Population. The author has an hindex of 58, co-authored 278 publications receiving 11996 citations. Previous affiliations of Umberto D'Alessandro include Medical Research Council & University of Antwerp.
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Journal ArticleDOI
Efficacy of Quinine, Artemether-Lumefantrine and Dihydroartemisinin-Piperaquine as Rescue Treatment for Uncomplicated Malaria in Ugandan Children
TL;DR: Recurrent infections observed after the administration of an ACT can be successfully treated with an alternative ACT rather than with quinine, as shown in a nested, randomized, open label, three-arm clinical trial of rescue therapy in children with recurrent malaria infection.
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Molecular markers of resistance to amodiaquine plus sulfadoxine–pyrimethamine in an area with seasonal malaria chemoprevention in south central Niger
Rebecca F. Grais,Ibrahim Maman Laminou,Lynda Woi-Messe,Rockyath Makarimi,Seidou H. Bouriema,Céline Langendorf,Alfred Amambua-Ngwa,Umberto D'Alessandro,Philippe J Guerin,Thierry Fandeur,Carol Hopkins Sibley +10 more
TL;DR: Although parasites with genotypes associated with the highest levels of resistance to AQ + SP are not yet common in this setting, their importance for deployment of SMC and IPTp dictates that monitoring of these markers of resistance should accompany these interventions.
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Consistent signatures of selection from genomic analysis of pairs of temporal and spatial Plasmodium falciparum populations from The Gambia
Alfred Amambua-Ngwa,David Jeffries,Roberto Amato,Archibald Worwui,Mane Karim,Sukai Ceesay,Haddy Nyang,Davis Nwakanma,Joseph Okebe,Dominic P. Kwiatkowski,David J. Conway,Umberto D'Alessandro +11 more
TL;DR: Genome sequences of 247 Plasmodium falciparum isolates collected in The Gambia in 2008 and 2014 were analysed to identify changes possibly related to the scale-up of antimalarial interventions that occurred during this period.
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Do hotspots fuel malaria transmission: a village-scale spatio-temporal analysis of a 2-year cohort study in The Gambia
Gillian Stresman,Julia Mwesigwa,Julia Mwesigwa,Jane Achan,Jane Achan,Emanuele Giorgi,Archibald Worwui,Archibald Worwui,Musa Jawara,Musa Jawara,Gian Luca Di Tanna,Teun Bousema,Jean-Pierre Van Geertruyden,Chris Drakeley,Umberto D'Alessandro,Umberto D'Alessandro +15 more
TL;DR: The findings support the notion of transmission occurring at the household and village scales but not the use of a targeted approach to interrupt spreading of infections from high to low burden areas within villages in this setting.
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Maternal anaemia as an indicator for monitoring malaria control in pregnancy in sub-Saharan Africa.
TL;DR: This data indicates that primigravidae are more susceptible to Plasmodium falciparum malaria and are at excess risk of malarial anaemia, which is a major problem in many developing countries and often occurs more frequently in first pregnancies.