U
Uwe Pichlmeier
Publications - 14
Citations - 4916
Uwe Pichlmeier is an academic researcher. The author has contributed to research in topics: Internal medicine & Medicine. The author has an hindex of 9, co-authored 10 publications receiving 4388 citations.
Papers
More filters
Journal ArticleDOI
Fluorescence-guided surgery with 5-aminolevulinic acid for resection of malignant glioma: a randomised controlled multicentre phase III trial.
Walter Stummer,Uwe Pichlmeier,Thomas Meinel,Otmar D. Wiestler,Friedhelm E. Zanella,Hans-Jürgen Reulen +5 more
TL;DR: Tumour fluorescence derived from 5-aminolevulinic acid enables more complete resections of contrast-enhancing tumour, leading to improved progression-free survival in patients with malignant glioma.
Journal ArticleDOI
Extent of resection and survival in glioblastoma multiforme: identification of and adjustment for bias.
Walter Stummer,Hanns-Jürgen Reulen,Thomas Meinel,Uwe Pichlmeier,Wiebke Schumacher,Jörg-Christian Tonn,Veit Rohde,Falk Oppel,Bernd Turowski,Christian Woiciechowsky,Kea Franz,Torsten Pietsch +11 more
TL;DR: The present data provide Level 2b evidence (Oxford Centre for Evidence-based Medicine) that survival depends on complete resection of enhancing tumor in glioblastoma multiforme and treatment bias was demonstrated regarding resection and second-line therapies.
Journal ArticleDOI
Resection and survival in glioblastoma multiforme: An RTOG recursive partitioning analysis of ALA study patients
TL;DR: Differences in survival depending on resection status, especially in RPA classes IV and V, support a causal influence of resection on survival.
Journal ArticleDOI
Counterbalancing risks and gains from extended resections in malignant glioma surgery: a supplemental analysis from the randomized 5-aminolevulinic acid glioma resection study. Clinical article
Walter Stummer,Jörg-Christian Tonn,Hubertus Maximilian Mehdorn,Ulf Nestler,Kea Franz,Claudia Goetz,Andrea Bink,Uwe Pichlmeier +7 more
TL;DR: Extended resections performed using a tool such as 5-ALA-derived tumor fluorescence, carries the risk of temporary impairment of neurological function, however, risks are higher in patients with deficits unresponsive to steroids.
Journal ArticleDOI
5-Aminolevulinic acid-derived tumor fluorescence: the diagnostic accuracy of visible fluorescence qualities as corroborated by spectrometry and histology and postoperative imaging.
Walter Stummer,Jörg-Christian Tonn,Claudia Goetz,Winfried Ullrich,Herbert Stepp,Andrea Bink,Thorsten Pietsch,Uwe Pichlmeier +7 more
TL;DR: Fluorescence appears superior to contrast enhancement on MRI for indicating residual tumor and spectrometry, on the other hand, is more sensitive but less specific, depending on threshold definition.