C
Christian Woiciechowsky
Researcher at Charité
Publications - 65
Citations - 3862
Christian Woiciechowsky is an academic researcher from Charité. The author has contributed to research in topics: Tumor necrosis factor alpha & Cytokine. The author has an hindex of 27, co-authored 64 publications receiving 3621 citations. Previous affiliations of Christian Woiciechowsky include Free University of Berlin & Humboldt University of Berlin.
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Journal ArticleDOI
Extent of resection and survival in glioblastoma multiforme: identification of and adjustment for bias.
Walter Stummer,Hanns-Jürgen Reulen,Thomas Meinel,Uwe Pichlmeier,Wiebke Schumacher,Jörg-Christian Tonn,Veit Rohde,Falk Oppel,Bernd Turowski,Christian Woiciechowsky,Kea Franz,Torsten Pietsch +11 more
TL;DR: The present data provide Level 2b evidence (Oxford Centre for Evidence-based Medicine) that survival depends on complete resection of enhancing tumor in glioblastoma multiforme and treatment bias was demonstrated regarding resection and second-line therapies.
Journal ArticleDOI
Sympathetic activation triggers systemic interleukin-10 release in immunodepression induced by brain injury.
Christian Woiciechowsky,Khusru Asadullah,D. Nestler,Beatrice Eberhardt,Cornelia Platzer,Cornelia Platzer,Britta Schöning,Frauke Glöckner,Wolfgang Lanksch,Hans-Dieter Volk,Wolf-Diatrich Döcke +10 more
TL;DR: It is found that in a rat model of acute brain injury, the βreceptor antagonist propranolol prevented the increase of interleukin-10 plasma levels and this may represent a common pathway for immunodepression induced by stress and injury.
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Topography of fibers in the human corpus callosum mediating interhemispheric inhibition between the motor cortices
TL;DR: The clinical findings suggest a role for TI in the performance of fast and complex hand motor tasks and characterize the system of callosal fibers activated by transcranial magnetic brain stimulation in more detail as a basis for a diagnostic application of this technique.
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Early IL-6 plasma concentrations correlate with severity of brain injury and pneumonia in brain-injured patients.
Christian Woiciechowsky,Britta Schöning,Jacqueline Cobanov,Wolfgang R. Lanksch,Hans-Dieter Volk,Wolf-Dieter Döcke +5 more
TL;DR: The IL-6 plasma level 1 day after the acute event with a cut-off of 100 pg/mL (Immulite) seems to be a predictor for short-term prognosis and infectious complications in brain-injured patients.
Journal ArticleDOI
Mechanisms of brain-mediated systemic anti-inflammatory syndrome causing immunodepression.
Christian Woiciechowsky,Britta Schöning,Wolfgang Lanksch,Hans-Dieter Volk,Wolf-Dietrich Döcke +4 more
TL;DR: Interestingly, cytokines in the brain and other stressors can also generate systemic immunodepression at the monocyte level and the catecholamine-induced release of the potent anti-inflammatory cytokine interleukin-10 is a newly discovered mechanism of the brain-mediated monocyte deactivation.