V
Vaishali A. Kulkarni
Researcher at Tata Institute of Fundamental Research
Publications - 4
Citations - 556
Vaishali A. Kulkarni is an academic researcher from Tata Institute of Fundamental Research. The author has contributed to research in topics: Dentate gyrus & Neurogenesis. The author has an hindex of 3, co-authored 4 publications receiving 508 citations. Previous affiliations of Vaishali A. Kulkarni include Rutgers University.
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The dendritic tree and brain disorders.
TL;DR: This review discusses dendritic development and branching, and in specific, morphology, cytoskeletal architecture, and how the complexity of the dendrite tree and its functional capabilities are altered in various brain disorders.
Journal ArticleDOI
Depletion of norepinephrine decreases the proliferation, but does not influence the survival and differentiation, of granule cell progenitors in the adult rat hippocampus.
TL;DR: The study indicates that depletion of norepinephrine by the selective noradrenergic neurotoxin, N‐(2‐chloroethyl)‐N‐ethyl‐2‐bromo benzylamine hydrochloride (DSP‐4), results in a 63% reduction in the proliferation of dentate gyrus progenitor cells identified through 5‐bomo‐2′‐deoxyuridine (BrdU) labelling.
Journal ArticleDOI
Antidepressant treatments regulate matrix metalloproteinases-2 and -9 (MMP-2/MMP-9) and tissue inhibitors of the metalloproteinases (TIMPS 1-4) in the adult rat hippocampus.
Madhurima Benekareddy,Purvi Mehrotra,Vaishali A. Kulkarni,Parvathy Ramakrishnan,Brian G. Dias,Vidita A. Vaidya +5 more
TL;DR: It is observed that acute and chronic ECS differentially regulate the transcript levels of MMP‐2/9 and TIMPs 1–4 and also increase gelatinase activity in the hippocampus and raises the possibility that extracellular matrix modifying enzymes and their endogenous regulators may serve as targets for antidepressant treatments.
SHORT COMMUNICATION Depletion of norepinephrine decreases the proliferation, but does not influence the survival and differentiation, of granule cell progenitors in the adult rat hippocampus
TL;DR: The study indicates that depletion of norepinephrine by the selective noradrenergic neurotoxin, N-(2-chloroethyl)-N-ethyl-2-bromobenzylamine hydrochloride (DSP-4), results in a 63% reduction in the proliferation of dentate gyrus progenitor cells identified through 5- bromo-2¢-deoxyuridine (BrdU) labelling.