V
Valentina Alda Carozzi
Researcher at University of Milano-Bicocca
Publications - 65
Citations - 2124
Valentina Alda Carozzi is an academic researcher from University of Milano-Bicocca. The author has contributed to research in topics: Peripheral neuropathy & Neurotoxicity. The author has an hindex of 22, co-authored 59 publications receiving 1732 citations. Previous affiliations of Valentina Alda Carozzi include University of Milan.
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Chemotherapy-induced peripheral neuropathy: What do we know about mechanisms?
TL;DR: The role of the main players in determining the pathogenesis of anticancer drugs-induced peripheral neuropathy is reviewed, with a focus on Dorsal Root Ganglia sensory neurons, satellite cells, Schwann cells and neuronal and glial cells in the spinal cord.
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Mitochondrial Dysfunction in Chemotherapy-Induced Peripheral Neuropathy (CIPN)
TL;DR: The expression of a certain number of genes, including those controlling mitochondrial functions, was altered in patients with bortezomib-induced peripheral neuropathy, and these genes were able to modify mitochondrial calcium homeostasis and mitochondrial respiratory chain.
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Multimodal assessment of painful peripheral neuropathy induced by chronic oxaliplatin-based chemotherapy in mice
Cynthia L. Renn,Valentina Alda Carozzi,Peter Rhee,Danisha Gallop,Susan G. Dorsey,Guido Cavaletti +5 more
TL;DR: It is demonstrated that chronic treatment with oxaliplatin produces neurotoxic changes in BALB/c mice, confirming that this model is a suitable tool to conduct further mechanistic studies of oxali platin-related antineoplastic activity, peripheral neurotoxicity and pain.
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Bortezomib-induced painful neuropathy in rats: a behavioral, neurophysiological and pathological study in rats.
Cristina Meregalli,Annalisa Canta,Valentina Alda Carozzi,Alessia Chiorazzi,Norberto Oggioni,Alessandra Gilardini,Cecilia Ceresa,F Avezza,Luca Crippa,Paola Marmiroli,Guido Cavaletti +10 more
TL;DR: An animal model of bortezomib‐induced nociceptive sensory neuropathy is developed and a severe reduction in nerve conduction velocity is induced and a dose‐cumulative effect of the drug is demonstrated.
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Bortezomib-induced painful peripheral neuropathy: an electrophysiological, behavioral, morphological and mechanistic study in the mouse
Valentina Alda Carozzi,Cynthia L. Renn,Michela Bardini,Grazia Fazio,Alessia Chiorazzi,Cristina Meregalli,Norberto Oggioni,Kathleen Shanks,Marina Quartu,Maria Pina Serra,B Sala,Guido Cavaletti,Susan G. Dorsey +12 more
TL;DR: It is found that bortezomib treatment induced morphological changes in the spinal cord, dorsal roots, dorsal root ganglia (DRG) and peripheral nerves, and the immune response is not a key factor in the development of morphological and functional damage induced by bortzomib in the peripheral nervous system.